IP Library › Granted Patent US 11,046,641
Granted Patent B2
US 11,046,641 · App. 15/593,864 · Granted Jun 29, 2021

Methods of treating fibrosis

Inventors: Sergio Baroni (Villa D'adda, IT); Salvatore Bellinvia (Mendrisio, CH); Francesca Viti (Salorino, CH)
Assignee: Nogra Pharma Limited
C07C229/44A61K31/196A61K31/343A61K31/357A61P1/04
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Quick Facts
Patent No.
US 11,046,641
App. No.
15/593,864
Granted
Jun 29, 2021
Kind
B2
Abstract

The present disclosure is directed in part to methods of treating fibrosis, e.g., hepatic fibrosis and/or intestinal fibrosis, comprising administering to a patient in need thereof an effective amount of a disclosed compound.

Claims (10)

1. A method of treating idiopathic pulmonary fibrosis, the method comprising administering to a patient in need thereof, a therapeutically effective amount of 2-methoxy-3-(4′-aminophenyl)-propionic acid,

or a pharmaceutically acceptable salt and/or a stereoisomer thereof.

2. The method of claim 1 , wherein the 2-methoxy-3-(4′-aminophenyl)propionic acid is (S)-2-methoxy-3-(4′-aminophenyl)propionic acid, or a pharmaceutically acceptable salt thereof.

3. The method of claim 1 , wherein the administering is orally.

4. The method of claim 1 , wherein the patient is human.

5. A method of treating idiopathic pulmonary fibrosis, the method comprising administering to a patient in need thereof, a pharmaceutical preparation comprising a therapeutically effective amount of 2-methoxy-3-(4′-aminophenyl)-propionic acid,

or a pharmaceutically acceptable salt and/or a stereoisomer thereof.

6. The method of claim 5 , wherein the pharmaceutical preparation is administered orally.

7. The method of claim 5 , wherein the patient is human.

8. The method of claim 5 , wherein the 2-methoxy-3-(4′-aminophenyl)propionic acid is (S)-2-methoxy-3-(4′-aminophenyl)propionic acid, or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 14, 2018
From: BARONI, SERGIO; BELLINVIA, SALVATORE; VITI, FRANCESCA
To: NOGRA PHARMA LIMITED
Reel/Frame 047778/0184 →
Priority Claims (1)
EP 12425027 · Feb 9, 2012 · regional
Continuity (3)
Division 14377362
Provisional Application 61644544 · May 9, 2012
Related Publication 20180065921A1 · Mar 8, 2018
Cited By (2)
US 12,291,494 US 12,509,416