Heart failure management
Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein.
1. A method, comprising:
delivering a heart failure (HF) therapy including electrical stimulation;
receiving parameter values from at least one HF-related parameter source;
generating at least a first HF status index and a second HF status index from the received parameter values; and
changing the electrical stimulation based on a combination of the first HF status index and the second HF index.
2. The method of claim 1 , further comprising generating at least a third HF status index from the received parameter values, and making another change to the electrical stimulation based on at least the third HF index.
3. The method of claim 1 , wherein delivering the HF therapy includes delivering electrical stimulation to heart muscle.
4. The method of claim 1 , wherein delivering the HF therapy includes delivering electrical stimulation to a neural target.
5. The method of claim 1 , wherein receiving parameter values includes receiving a heart rate variability (HRV) measurement, and generating includes generating at least the first HF status index using the measured HRV measurement.
6. The method of claim 1 , wherein receiving parameter values includes receiving a heart rate turbulence (HRT) measurement, and generating includes generating at least the first HF status index using the measured HRT measurement.
7. The method of claim 1 , wherein receiving parameter values includes receiving a respiration measurement, and generating includes generating at least the first HF status index using the measured respiration measurement.
8. The method of claim 1 , wherein receiving parameter values includes receiving an activity measurement, and generating includes generating at least the first HF status index using the activity measurement.
9. The method of claim 1 , wherein receiving parameter values includes receiving a heart sound measurement, and generating includes generating at least the first HF status index using the heart sound measurement.
10. The method of claim 1 , wherein receiving parameter values includes receiving a blood pressure measurement, and generating includes generating at least the first HF status index using the blood pressure measurement.
11. The method of claim 1 , wherein receiving parameter values includes receiving parameter values from one or more data source types selected from a group of data source types consisting of: a sensor data source type, a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
12. The method of claim 1 , wherein receiving parameter values includes receiving parameter values from:
a sensor data source type; and
one or more data source types selected from a group of data source types consisting of: a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
13. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to:
deliver a heart failure (HF) therapy including electrical stimulation;
receive parameter values from at least one HF-related parameter source;
generate at least a first HF status index and a second HF status index from the received parameter values; and
change the electrical stimulation based on a combination of the first HF status index and the second HF index.
14. The non-transitory machine-readable medium of claim 13 , further comprising instructions, which when executed by the machine, cause the machine to generate at least a third HF status index from the received parameter values, and make another change to the electrical stimulation based on at least the third HF index.
15. The non-transitory machine-readable medium of claim 13 , wherein receive parameter values includes receive parameter values from one or more data source types selected from a group of data source types consisting of: a sensor data source type, a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
16. The non-transitory machine-readable medium of claim 13 , wherein receive parameter values includes receive parameter values from:
a sensor data source type; and
one or more data source types selected from a group of data source types consisting of: a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
17. A system, comprising:
an implantable heart failure therapy delivery system configured to deliver a heart failure (HF) therapy including electrical stimulation; and
control circuitry operably connected to the heart failure therapy delivery system and configured to:
receive parameter values from at least one HF-related parameter source;
generate at least a first HF status index and a second HF status index from the received parameter values; and
change the electrical stimulation based on a combination of at least the first HF status index and the second HF status index.
18. The system of claim 17 , wherein the control circuitry is configured to generate at least a third HF status index from the received parameter values, and make another change to the electrical stimulation based on at least the third HF index.
19. The system of claim 17 , wherein the control circuitry is configured to receive parameter values from one or more data source types selected from a group of data source types consisting of: a sensor data source type, a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.
20. The system of claim 17 , wherein the control circuitry is configured to receive parameter values from:
a sensor data source type; and
one or more data source types selected from a group of data source types consisting of: a physician input data source type, a patient input data source type, a patient history data source type, a pharmaceutical data source type, and a population/clinical study data source type.