IP Library Granted Patent US 10,213,624
Granted Patent B2
US 10,213,624 · App. 15/705,437 · Granted Feb 26, 2019

Guided charged particle imaging/treatment apparatus and method of use thereof

Inventors: W. Davis Lee (Newburyport, MA); Mark R. Amato (South Hamilton, MA); Susan L. Michaud (Brewster, MA)
A61N5/1065A61B6/032A61B6/4092A61B6/4216A61B6/4258A61B6/4266A61N5/1037A61N5/1039A61N5/1044A61N5/1067A61N5/1069A61N5/1077A61N5/1082G21K1/08G21K5/04A61B6/467A61B6/5205A61N5/107A61N2005/1054A61N2005/1087A61N2005/1095A61N2005/1097
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Quick Facts
Patent No.
US 10,213,624
App. No.
15/705,437
Granted
Feb 26, 2019
Kind
B2
Abstract

The invention comprises a method and apparatus for tracking and/or imaging impact of a particle beam treating a tumor using one or more imaging systems positionable about the tumor, such as a positron emission tracking and/or imaging system, where resulting tracking/imaging data: dynamically determines a treatment beam position, tracks a history of treatment beam positions, guides the treatment beam, and/or images a tumor before, during, and/or after treatment with the charged particle beam.

Claims (57)

1. A method for imaging a tumor of a patient and treating the tumor with positively charged particles, comprising the steps of:

transporting the positively charged particles from a synchrotron, along a beam transport line, and through an exit nozzle system to a treatment beam path;

imaging the tumor using an imaging system, said step of imaging the tumor further comprising the steps of:

rotating a rotatable ring around a longitudinal axis of the patient;

rotating said imaging system around the patient using rotation of said rotatable ring; and

translating, through relative motion of the patient and said imaging system mounted to said rotatable ring, said imaging system past the tumor; and

controlling the treatment beam path using image data from said imaging system.

2. The method of claim 1 , said step of rotating said rotatable ring around the longitudinal axis of the patient further comprising the step of:

maintaining an imaging source and an imaging detector of said imaging system on opposite sides of the patient.

3. The method of claim 2 , said step of translating said imaging system past the tumor further comprising the step of:

maintaining position of the patient along an axis between said imaging source and said imaging detector.

4. The method of claim 3 , further comprising the step of:

along at least one axis, independently moving said imaging system and the patient.

5. The method of claim 4 , further comprising the step of:

independently rotating: (1) said rotatable ring and (2) a gantry supporting at least a portion of said beam transport line and said exit nozzle system.

6. The method of claim 3 , further comprising the step:

a main controller device automatically treating the tumor using both: (1) said step of imaging the tumor and (2) said step of transporting the positively charged particles.

7. The method of claim 6 , further comprising the step of:

generating a computed tomography image of the tumor using the image data.

8. The method of claim 3 , further comprising the step of:

using a patient positioning system to position the patient relative to said rotatable ring.

9. The method of claim 8 , said step of using said patient positioning system further comprising the step of:

positioning the patient relative to said exit nozzle system.

10. The method of claim 1 , further comprising the step of:

rotating said exit nozzle system around the longitudinal axis of the patient.

11. The method of claim 10 , further comprising the steps of:

retracting said imaging system toward said rotatable ring;

treating the tumor using the positively charged particles; and

extending said imaging system past the patient.

12. The method of claim 10 , further comprising the steps of:

sequentially performing a set of steps, comprising:

extending said imaging system away from said rotatable ring;

performing said step of imaging the tumor using said imaging system;

retracting said first imaging system toward said rotatable ring; and

treating the tumor using the positively charged particles.

13. The method of claim 12 , further comprising the step of:

a main controller repeating said set of steps to monitor treatment of the tumor.

14. The method of claim 13 , further comprising the step of:

said main controller automatically controlling treatment of the tumor.

15. The method of claim 14 , further comprising the steps of:

generating a proton beam computed tomography image of the tumor using the positively charged particles; and

overlaying the proton beam computed tomography image of the tumor and an X-ray computed tomography image generated using said imaging system.

16. The method of claim 1 , further comprising the step of:

a main controller automatically dynamically altering an irradiation plan of the tumor using the image data and control of an extraction energy of the positively charged particles from said synchrotron.

17. The method of claim 1 , said step of imaging further comprising the step of:

generating the image data elements along a set of paths both parallel to and corresponding to elements of a set of treatment paths as a function of gantry rotation of said exit nozzle system around the patient.

18. An apparatus for imaging and treating a tumor of a patient with positively charged particles, comprising:

a treatment beam path from a synchrotron, along a beam transport line, and through a nozzle system;

an imaging system, comprising:

a rotatable ring around a longitudinal axis of a laying patient position;

an imaging system mounted indirectly to said rotatable ring, said rotatable ring configured to rotate said imaging system around the patient during use; and

said imaging system mounted to said rotatable ring using a set of mounting rails, said imaging system configured to translate, through relative motion of the patient and said imaging system mounted to said rotatable ring, past the tumor during use; and

a main controller configured to control the treatment beam path using image data from said imaging system during use.

19. The apparatus of claim 18 , said mounting rails configured to:

maintain an imaging source and an imaging detector of said imaging system on opposite sides of the patient: (1) during rotation of said rotatable ring and (2) with relative linear translation motion of a patient position and said rotatable ring.

20. The apparatus of claim 19 , further comprising:

a main controller device configured to automatically treat the tumor using both: (1) the image data and (2) control of the treatment beam path.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2023
From: LEE, W DAVIS; AMATO, MARK R; MICHAUD, SUSAN L
To: PROTOM INTERNATIONAL HOLDING CORPORATION
Reel/Frame 062378/0158 →
Continuity (23)
Continuation 15281031 · Sep 29, 2016
Continuation In Part 15167617 · May 27, 2016
Continuation In Part 15152479 · May 11, 2016
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13087096 · Apr 14, 2011
Continuation In Part 13788890 · Mar 7, 2013
Continuation In Part 14952817 · Nov 25, 2015
Continuation In Part 14293861 · Jun 2, 2014
Continuation In Part 12985039 · Jan 5, 2011
Continuation In Part 14860577 · Sep 21, 2015
Continuation 14223289 · Mar 24, 2014
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 12985039 · Jan 5, 2011
Continuation In Part 15073471 · Mar 17, 2016
Continuation In Part 14860577 · Sep 21, 2015
Continuation 14223289 · Mar 24, 2014
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13572542 · Aug 10, 2012
Continuation In Part 12425683 · Apr 17, 2009
Provisional Application 61055395 · May 22, 2008
Provisional Application 62304839 · Mar 7, 2016
Provisional Application 61324776 · Apr 16, 2010
Related Publication 20180001110A1 · Jan 4, 2018
Cited By (1)
US 12,245,355