Methods for treating sarcopenia and frailty
Neuregulin-1 (NRG1) or a fragment thereof or vitamin B12 for use in maintaining or increasing muscle function and/or mass in an ageing subject, and/or substantially preventing or reducing muscle wasting in an ageing subject.
1. A method of maintaining or increasing muscle function and/or mass in an ageing subject over thirty years old, the method comprising administering neuregulin-1 (NRG1) comprising the amino acid sequence of SEQ. ID. NO. 6 to the ageing subject.
2. The method of claim 1 , wherein the method further comprises administering vitamin B12 to the ageing subject in need thereof.
3. The method of claim 2 , wherein the vitamin B12 comprises at least one of adenosylcobalamin or methylcobalamin.
4. A method of treating sarcopenia or frailty, the method comprising administering neuregulin-1 (NRG1) comprising the amino acid sequence of SEQ. ID. NO. 6 to a subject in need thereof.
5. The method of claim 4 , wherein the method further comprises administering vitamin B12 to the subject in need thereof.
6. The method of claim 5 , wherein the vitamin B12 is at least one of adenosylcobalamin or methylcobalamin.