Prodrugs of fumarates and their use in treating various diseases
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
1. A crystalline form of a compound having the formula:
having an X-ray powder diffraction pattern comprising peaks, in terms of degrees 2-theta±0.2 degrees, at 11.6, 21.0, 24.3, 27.4, and 27.9 when using a Cu X-ray source.
2. A pharmaceutical composition comprising a crystalline form of claim 1 and a pharmaceutically acceptable carrier.
3. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a crystalline form of claim 1 .
4. A method of treating multiple sclerosis in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a composition of claim 2 .