IP Library Granted Patent US 11,278,476
Granted Patent B2
US 11,278,476 · App. 15/790,903 · Granted Mar 22, 2022

Electromagnetic radiation and delivery carrier for oral care

Inventors: Jayanth Rajaiah (Loveland, OH); Paul Albert Sagel (Mainville, OH); Franco Silva Medeiros (Loveland, OH)
Assignee: The Procter & Gamble Company
A61K8/064A61C19/066A61K8/0216A61K8/062A61K8/22A61K8/31A61K8/345A61K8/8111A61K8/86A61K8/92A61N5/062A61N5/0603A61Q11/00A61Q11/02A61K2800/42A61K2800/81A61K2800/87A61K2800/884A61K2800/92A61N2005/0606A61N2005/0663
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Quick Facts
Patent No.
US 11,278,476
App. No.
15/790,903
Granted
Mar 22, 2022
Kind
B2
Abstract

Delivery carriers having multi-phase oral compositions used with an electromagnetic radiation source for whitening teeth.

Claims (28)

1. A kit comprising:

a) a delivery carrier selected from the group consisting of a strip, a dental tray, a sponge material, and combinations thereof,

b) a multi-phase oral composition for whitening teeth, comprising:

i. from about 0.002% to about 30%, by weight of the multi-phase oral composition, of a discontinuous aqueous phase having a bleaching agent; and

ii. at least about 50%, by weight of the multi-phase oral composition, of a continuous hydrophobic phase of petrolatum; and

c) an electromagnetic radiation source capable of directing electromagnetic radiation with one or more wavelength in the range from about 200 nm to about 1700 nm toward at least one tooth; and

wherein the concentration of the bleaching agent is up to 10%, by weight of the multi-phase oral composition;

wherein the multi-phase oral composition is a water-in oil emulsion.

2. The kit according to claim 1 , wherein the ratio of the concentration in weight percent of bleaching agent present in the aqueous phase to the concentration in weight percent of bleaching agent present in the overall multi-phase oral composition is at least about 10.

3. The kit according to claim 2 , wherein the ratio of the concentration in weight percent of bleaching agent present in the aqueous phase to the concentration in weight percent of bleaching agent present in the overall multi-phase oral composition is at least about 50.

4. The kit according to claim 1 , wherein the amount of the bleaching agent ranges from about 0.01% to about 0.095% by weight of the multi-phase oral composition.

5. The kit according to claim 1 , wherein the cone penetration consistency value of the hydrophobic phase or the multiphase oral composition is from about 100 to about 300, as measured by ASTM D937-07.

6. The kit according to claim 5 , wherein the cone penetration consistency value of the hydrophobic phase or the multiphase oral composition is from about 100 to about 250, as measured by ASTM D937-07.

7. The kit according to claim 1 , wherein the drop melting point of the hydrophobic phase is from about 40° C. to about 80° C., as measured by ASTM D127-08.

8. The kit according to claim 1 , wherein the two-dimensional density of droplets with a cross-sectional area larger than about 10000 square microns measured using the procedure specified herein is no more than about 20 per square centimeter.

9. The kit according to claim 8 , wherein the two-dimensional density of droplets with a cross-sectional area larger than about 10000 square microns measured using the procedure specified herein is no more than about 10 per square centimeter.

10. The kit according to claim 1 , wherein the bleaching agent is a peroxide bleaching agent, and wherein the standard deviation of the peroxide concentration of the multi-phase oral composition smeared onto peroxide test strips measured using the procedure specified herein is no more than about 50.

11. The kit according to claim 10 , wherein the standard deviation of the peroxide concentration of the multi-phase oral composition smeared onto peroxide test strips measured using the procedure specified herein is no more than about 25.

12. The kit according to claim 1 , wherein the bleaching agent is a peroxide bleaching agent, and wherein the mean residual peroxide concentration of the multi-phase oral composition smeared onto peroxide test strips measured using the procedure specified herein is from about 1 to about 100.

13. The kit according to claim 12 , wherein the mean residual peroxide concentration of the multi-phase oral composition smeared on teeth measured using the procedure specified herein is from about 20 to about 200.

14. The kit according to claim 1 , wherein the bleaching agent in the multi-phase oral composition comprises hydrogen peroxide.

15. The kit according to claim 1 , wherein the bleaching efficacy of the multi-phase oral composition calculated as −Δb* and measured per the clinical protocol as disclosed herein is at least about 1.5.

16. The kit according to claim 1 , wherein the ratio of the bleaching efficacy of the multi-phase oral composition calculated as −Δb* and measured per the clinical protocol as disclosed herein to the weight percentage of bleaching agent present in the overall multi-phase oral composition is at least about 1.5.

17. The kit according to claim 1 wherein the delivery carrier is a dental tray.

18. The kit according to claim 1 wherein the delivery carrier is a strip, wherein the strip is deformable and made of plastic or wax.

19. The kit according to claim 17 , wherein the electromagnetic radiation source emits electromagnetic radiation in the range from about 400 nm to about 500 nm, impinging on the outer surface of the delivery carrier at least one tooth, in the range from about 175 mW/cm2 to about 225 mW/cm2 measured using the procedures described herein.

20. The kit according to claim 1 , wherein the discontinuous aqueous phase is dispersed as droplets within the continuous hydrophobic phase.

21. The kit according to claim 1 , wherein the multi-phase oral composition comprises from 0% to about 0.5%, by weight of the multi-phase oral composition, of emulsifier.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 9, 2021
From: MEDEIROS, FRANCO SILVA
To: THE PROCTER & GAMBLE COMPANY
Reel/Frame 058058/0197 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2019
From: RAJAIAH, JAYANTH (NMN); SAGEL, PAUL ALBERT
To: THE PROCTER & GAMBLE COMPANY
Reel/Frame 048240/0014 →
Continuity (8)
Provisional Application 62413214 · Oct 26, 2016
Provisional Application 62413237 · Oct 26, 2016
Provisional Application 62413222 · Oct 26, 2016
Provisional Application 62413229 · Oct 26, 2016
Provisional Application 62413200 · Oct 26, 2016
Provisional Application 62413189 · Oct 26, 2016
Provisional Application 62413205 · Oct 26, 2016
Related Publication 20180133128A1 · May 17, 2018
Cited By (4)
US 12,337,044 US 12,447,115 US 12,496,262 US 12,551,414