IP Library › Granted Patent US 12,551,414
Granted Patent B2
US 12,551,414 · App. 17/738,047 · Granted Feb 17, 2026

Systems and methods for delivering active agents

Inventors: Jayanth Rajaiah (Loveland, OH); Paul Albert Sagel (Maineville, OH); Geoffrey Marc Wise (Reading, OH)
Assignee: The Procter & Gamble Company
A61K8/062A61K8/37A61K8/463A61K8/678A61Q11/00A61K8/064A61K2800/10A61K2800/81A61K2800/92
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Quick Facts
Patent No.
US 12,551,414
App. No.
17/738,047
Granted
Feb 17, 2026
Kind
B2
Abstract

A system for delivering an active agent comprising an oral care composition, a delivery carrier, and optionally a device capable of producing electromagnetic radiation. The oral care composition can include a high internal phase oil-in-water emulsion and/or jammed oil-in-water emulsion. A method for delivering an active agent to an oral cavity including providing an oral care composition, contacting the oral care composition with at least one tooth, and optionally applying electromagnetic radiation to at least one tooth.

Claims (23)

1 . A system for delivering an active agent to an oral cavity comprising:

(a) an oral care composition comprising a jammed oil-in water emulsion, wherein the jammed oil-in-water emulsion exhibits no more than 5% macroscopic separation after 48 hours at 23° C., the jammed oil-in-water emulsion comprising:

(i) from 1% to 15%, by weight of the jammed oil-in water emulsion, of an at least partially continuous aqueous phase,

(ii) a discontinuous hydrophobic phase,

(iii) the active agent, and

(iv) an emulsifier, wherein the emulsifier comprises polysorbate 20, polysorbate 40, sodium lauryl sulfate, or combinations thereof; and

(b) a delivery carrier.

2 . The system of claim 1 , wherein the system further comprises a device capable of producing electromagnetic radiation.

3 . The system of claim 1 , wherein the oral care composition comprises from about 80% to about 99%, by weight of the composition, of the discontinuous hydrophobic phase.

4 . The system of claim 1 , wherein the oral care composition comprises from about 85% to about 95%, by weight of the composition, of the discontinuous hydrophobic phase.

5 . The system of claim 1 , wherein the oral care composition comprises from about 5% to about 15%, by weight of the composition, of the at least partially continuous aqueous phase.

6 . The system of claim 1 , wherein the oral care composition comprises from about 85% to about 95%, by weight of the composition, of the discontinuous hydrophobic phase and from about 5% to about 15%, by weight of the composition, of the at least partially continuous aqueous phase.

7 . The system of claim 1 , wherein the at least partially continuous aqueous phase comprises the active agent.

8 . The system of claim 1 , wherein the discontinuous hydrophobic phase comprises the active agent.

9 . The system of claim 1 , wherein the active agent comprises a bleaching agent, an anti-caries agent, an anti-tartar agent, a remineralization agent, a wound healing agent, an anti-inflammatory agent, an antibacterial agent, a metal ion source, an anti-glycolytic agent, an amino acid, a probiotic, a prebiotic, a postbiotic, a polyphosphate, a buffer, an anti-sensitivity agent, or combinations thereof.

10 . The system of claim 1 , wherein the active agent comprises a bleaching agent, a vitamin, or combinations thereof.

11 . The system of claim 1 , wherein the oral care composition comprises from about 0.01% to about 10%, by weight of the composition, of the emulsifier.

12 . The system of claim 1 , wherein the emulsifier comprises one or more hydrophobic tails, the one or more hydrophobic tails having from about 6 to about 20 carbon atoms.

13 . The system of claim 12 , wherein the one or more hydrophobic tails has up to 4 branches.

14 . The system of claim 2 , wherein the electromagnetic radiation has a wavelength of from 1 nm to 1 mm.

15 . The system of claim 2 , wherein the electromagnetic radiation has a wavelength of from about 100 nm to 900 nm.

16 . The system of claim 1 , wherein the delivery carrier comprises a tray, a strip, or a combination thereof.

17 . The system of claim 1 , wherein the discontinuous hydrophobic phase comprises at least 84%, by weight of the jammed oil-in water emulsion, of petrolatum, mineral oil, or a combination thereof.

Continuity (3)
Continuation 16850037 · Apr 16, 2020
Provisional Application 62838369 · Apr 25, 2019
Related Publication 20220347064A1 · Nov 3, 2022
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