Rinseable multi-phase compositions
A multi-phase oral composition with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier, which is rinseable from a surface and/or has a high water dispersibility. A jammed oil-in-water composition with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier, which is rinseable from a surface and/or has a high water dispersibility. Methods of using disclosed compositions for active agent delivery.
1. A jammed oil-in-water emulsion comprising:
(a) at least partially continuous aqueous phase;
(b) discontinuous hydrophobic phase; and
(c) oral care active agent,
wherein the jammed oil-in-water emulsion has a yield stress greater than a yield stress of the hydrophobic phase and a yield stress of the aqueous phase.
2. The emulsion of claim 1 , wherein the yield stress of the jammed oil-in-water emulsion is from about 2 Pa to about 2000 Pa at 23° C.
3. The emulsion of claim 1 , wherein the yield stress of the jammed oil-in-water emulsion is from about 2 Pa to about 500 Pa at 23° C.
4. The emulsion of claim 1 , wherein the yield stress of the jammed oil-in-water emulsion is from about 2 Pa to about 250 Pa at 23° C.
5. The emulsion of claim 1 , wherein the oral care active agent comprises anti-caries agent, antimicrobial agent, whitening agent, or combinations thereof.
6. The emulsion of claim 5 , wherein the anti-caries agent comprises amino acid, fluoride, or combinations thereof.
7. The emulsion of claim 6 , wherein the amino acid comprises histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, alanine, asparagine, aspartic acid, glutamic acid, arginine, cysteine, glutamine, tyrosine, glycine, ornithine, proline, serine, or combinations thereof.
8. The emulsion of claim 6 , wherein the fluoride comprises sodium fluoride, potassium fluoride, titanium fluoride, hydrofluoric acid, amine fluoride, sodium monofluorophosphate, stannous fluoride, or combinations thereof.
9. The emulsion of claim 5 , wherein the antimicrobial agent comprises metal ion source, the metal ion source comprises stannous, zinc, copper, or combinations thereof.
10. The emulsion of claim 5 , wherein the whitening agent comprises peroxide.
11. The emulsion of claim 10 , wherein the peroxide comprises hydrogen peroxide, urea peroxide, calcium peroxide, carbamide peroxide, or combinations thereof.
12. The emulsion of claim 1 , wherein the emulsion comprises from about 85% to about 95%, by weight of the emulsion, of the hydrophobic phase.
13. The emulsion of claim 1 , wherein the emulsion comprises from about 5% to about 15%, by weight of the emulsion, of the aqueous phase.
14. The emulsion of claim 1 , wherein the emulsion comprises from about 0.01% to about 10%, by weight of the emulsion, of the oral care active agent.
15. The emulsion of claim 1 , wherein the emulsion comprises from about 0.01% to about 10%, by weight of the emulsion, of emulsifier.
16. The emulsion of claim 15 , wherein the emulsifier is a polysorbate, an alkyl sulfate, or combinations thereof.
17. The emulsion of claim 16 , wherein the alkyl sulfate comprises sodium lauryl sulfate.
18. The emulsion of claim 16 , wherein the emulsion is free of the alkyl sulfate.
19. The emulsion of claim 1 , wherein the emulsion is free of abrasive.
20. The emulsion of claim 1 , wherein the emulsion comprises fluoride and peroxide.