Compositions and methods for treatment of cardiovascular disorders
ECM based compositions including acellular ECM and antibiotics, and methods for employing same to treat damaged cardiovascular tissue and, thereby, disorders.
1. A method of treating infarcted cardiovascular tissue of a subject, the method comprising the steps of:
providing a particulate structure consisting of a mixed liquid consisting of a particulate acellular extracellular matrix (ECM) from mammalian heart tissue, vancomycin and gentamicin, said particulate structure inducing neovascularization and remodeling of infarcted cardiovascular tissue, and regeneration of new cardiovascular tissue and tissue structures with site specific structural and functional properties when said particulate structure is delivered to said infarcted cardiovascular tissue; and
delivering a therapeutically effective amount of said particulate structure directly to said infarcted cardiovascular tissue of said subject.