IP Library › Granted Patent US 10,213,505
Granted Patent B2
US 10,213,505 · App. 15/937,784 · Granted Feb 26, 2019

Anti-TIGIT anibodies, anti-PVRIG antibodies and combinations thereof

Inventors: Mark White (Antioch, CA); Sandeep Kumar (San Bruno, CA); Christopher Chan (South San Francisco, CA); Spencer Liang (San Mateo, CA); Lance Stapleton (Oakland, CA); Andrew W. Drake (Mountain View, CA); Yosi Gozlan (Tel Aviv, IL); Ilan Vaknin (Tel Aviv, IL); Shirley Sameah-Greenwald (Kfar Saba, IL); Liat Dassa (Tel Aviv, IL); Zohar Tiran (Oranit, IL); Gad S. Cojocaru (Tel Aviv, IL); Maya Kotturi (Belmont, CA); Hsin-Yuan Cheng (San Mateo, CA); Kyle Hansen (San Francisco, CA); David Nisim Giladi (Netaniya, IL); Einav Safyon (Raanana, IL); Eran Ophir (Even Yehuda, IL); Leonard Presta (San Francisco, CA); Richard Theolis (Santa Cruz, CA); Radhika Desai (Brisbane, CA); Patrick Wall (Mill Valley, CA)
Assignee: Compugen Ltd.
A61K39/39558A61K39/39541C07K16/2803C07K16/2818C07K16/2827A61K2039/505A61K2039/507C07K2317/21C07K2317/24C07K2317/33C07K2317/34C07K2317/524C07K2317/526C07K2317/53C07K2317/56C07K2317/732C07K2317/76C07K2317/92C07K2319/035C07K2319/33
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Quick Facts
Patent No.
US 10,213,505
App. No.
15/937,784
Granted
Feb 26, 2019
Kind
B2
Abstract

Anti-PVRIG and anti-TIGIT antibodies are provided.

Claims (6)

1. A composition comprising an anti-PVRIG antibody, wherein said antibody comprises:

i) a heavy chain comprising SEQ ID NO:9, and

ii) a light chain comprising SEQ ID NO:14.

2. A composition comprising an anti-PVRIG antibody, wherein said antibody comprises:

i) a heavy chain comprising SEQ ID NO:19, and

ii) a light chain comprising SEQ ID NO:24.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2018
From: GOZLAN, YOSI; VAKNIN, ILAN; SAMEAH-GREENWALD, SHIRLEY; DASSA, LIAT; TIRAN, ZOHAR; COJOCARU, GAD S.; GILADI, DAVID NISIM; SAFYON, EINAV; OPHIR, ERAN
To: COMPUGEN LTD.
Reel/Frame 046685/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2018
From: PRESTA, LEONARD
To: COMPUGEN LTD.
Reel/Frame 046685/0790 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2018
From: WHITE, MARK; KUMAR, SANDEEP; CHAN, CHRISTOPHER; LIANG, SPENCER; STAPLETON, LANCE; DRAKE, ANDREW W.; KOTTURI, MAYA; CHENG, HSIN-YUANG; HANSEN, KYLE; THEOLIS, RICHARD; DESAI, RADHIKA; WALL, PATRICK
To: COMPUGEN USA, INC.
Reel/Frame 046687/0320 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2018
From: COMPUGEN USA, INC.
To: COMPUGEN LTD.
Reel/Frame 046687/0507 →
Continuity (11)
Division 15795135 · Oct 26, 2017
Division 15680187 · Aug 17, 2017
Provisional Application 62376335 · Aug 17, 2016
Provisional Application 62417217 · Nov 3, 2016
Provisional Application 62513775 · Jun 1, 2017
Provisional Application 62477974 · Mar 28, 2017
Provisional Application 62513916 · Jun 1, 2017
Provisional Application 62538561 · Jul 28, 2017
Provisional Application 62376334 · Aug 17, 2016
Provisional Application 62513771 · Jun 1, 2017
Related Publication 20180280506A1 · Oct 4, 2018
Cited By (2)
US 12,570,744 US 12,735,483