Compositions and methods for controlling nematodes
Compositions and methods for controlling nematodes are described herein, e.g., nematodes that infest plants or animals. The compounds include oxazoles, oxadiazoles and thiadiazoles.
1. A treated seed comprising a nematicidal composition comprising a compound of Formula I, Formula II, or a salt thereof,
wherein,
A is phenyl or pyrazyl, each of which can be optionally independently substituted with one or more substituents selected from the group consisting of halogen, CF 3 , CH 3 , OCF 3 , OCH 3 , CN and C(H)O;
B is C(H) or C(CH 3 ); and
C is furanyl, oxazolyl, or isoxazolyl, each of which can be optionally independently substituted with one or more substituents selected from the group consisting of fluorine, chlorine, CH 3 , and OCF 3 .
2. The seed of claim 1 wherein A is phenyl.
3. The seed of claim 1 wherein A is pyrazyl.
4. The seed of claim 1 wherein B is C(H).
5. The seed of claim 1 wherein B is C(CH 3 ).
6. The seed of claim 1 wherein C is furanyl.
7. The seed of claim 1 wherein C is oxazolyl.
8. The seed of claim 1 wherein C is isoxazolyl.
9. The seed of claim 1 wherein the composition comprises a compound of Formula Ia or a salt thereof,
wherein,
R 1 and R 5 are independently selected from the group consisting of hydrogen, CH 3 , F, Cl, Br, CF 3 , and OCF 3 R 2 and R 4 are independently selected from the group consisting of hydrogen, F, Cl, Br, and CF 3 ;
R 3 is selected from hydrogen, CH 3 , CF 3 , F, Cl, Br, OCF 3 , OCH 3 , CN, and C(H)O;
R 7 and R 8 are independently selected from the group consisting of hydrogen and fluorine;
R 9 is selected from the group consisting of hydrogen, F, Cl, CH 3 , and OCF 3 ;
B is C(H) or C(CH 3 ); and
E is O.
10. The seed of claim 1 wherein the composition comprises a compound of Formula Ib or a salt thereof,
wherein,
R 1 and R 5 are independently selected from the group consisting of hydrogen, CH 3 , F, Cl, Br, CF 3 , and OCF 3 ;
R 2 and R 4 are independently selected from the group consisting of hydrogen, F, Cl, Br, and CF 3 ;
R 3 is selected from the group consisting of hydrogen, CH 3 , CF 3 , F, Cl, Br, OCF 3 , OCH 3 , CN, and C(H)O;
R 8 is selected from the group consisting of hydrogen and fluorine;
R 6 and R 9 are independently selected from the group consisting of hydrogen, F, Cl, CH 3 , and OCF 3 ;
B is C(H) or C(CH 3 ); and
E is O.
11. The seed of claim 1 wherein the composition comprises a compound of Formula IIa or a salt thereof,
wherein,
R 1 and R 5 are independently selected from the group consisting of hydrogen, CH 3 , F, Cl, Br, CF 3 and OCF 3 ; R 2 and R 4 are independently selected from the group consisting of hydrogen, F, Cl, Br, and CF 3 ;
R 3 is selected from the group consisting of hydrogen, CH 3 , CF 3 , F, Cl, Br, OCF 3 , OCH 3 , CN, and C(H)O;
R 7 and R 8 are independently selected from the group consisting of hydrogen and F;
R 9 is selected from the group consisting of hydrogen, F, Cl, CH 3 , and OCF 3 ;
B is C(H) or C(CH 3 ); and
E is O.
12. The seed of claim 1 wherein the composition comprises a compound of Formula IIb or a salt thereof,
wherein,
R 1 and R 5 are independently selected from the group consisting of hydrogen, CH 3 , F, Cl, Br, CF 3 and OCF 3 ;
R 2 and R 4 are independently selected from the group consisting of hydrogen, F, Cl, Br and CF 3 ;
R 3 is selected from the group consisting of hydrogen, CH 3 , CF 3 , F, Cl, Br, OCF 3 , OCH 3 , CN and C(H)O;
R 8 is selected from the group consisting of hydrogen and fluorine;
R 6 and R 9 are independently selected from the group consisting of hydrogen, F, Cl, CH 3 and OCF 3 ;
B is C(H) or C(CH 3 ); and
E is O.
13. The seed of claim 1 wherein the composition comprises a compound selected from the group consisting of:
5-(4-fluorophenyl)-2-(furan-2-yl)oxazole; and
5-(4-chlorophenyl)-2-(furan-3-yl)oxazole.
14. The seed of claim 1 wherein the composition improves one or more agronomic characteristics of a plant.
15. The seed of claim 14 wherein the one or more agronomic characteristics comprises vigor.