IP Library › Granted Patent US 10,767,179
Granted Patent B2
US 10,767,179 · App. 16/148,466 · Granted Sep 8, 2020

MicroRNA composition for the treatment of neuroblastoma

Inventor: Liqin Du (San Antonio, TX)
Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
C12N15/113A61K31/713A61K45/06C12N2310/141
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,767,179
App. No.
16/148,466
Granted
Sep 8, 2020
Kind
B2
Abstract

Certain embodiments are directed to methods of identifying neuroblastoma differentiation-inducing compounds or agent and their use in treating neuroblastoma.

Claims (3)

1. A synthetic microRNA mimic comprising a double stranded RNA comprising (i) a first RNA component comprising a seed sequence of aaggcac (SEQ ID NO:3) and a mature sequence that is at least 90% identical to uaaggcacccuucugaguaga (SEQ ID NO:1), and (ii) a second RNA component comprising a complement of the first RNA component.

2. The synthetic microRNA mimic of claim 1 , wherein the mimic is at most 150 nucleotides in length.

3. The synthetic microRNA mimic of claim 1 , wherein the mimic is 30 to 130 nucleotides in length.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2018
From: DU, LUQIN
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 047022/0798 →
Continuity (3)
Continuation 15118551
Provisional Application 61939730 · Feb 13, 2014
Related Publication 20190062745A1 · Feb 28, 2019