Platelet lysate gel
The invention concerns a pharmaceutical composition comprising a platelet lysate and its use to treat a wound, an anal fissure, vaginal atrophy or a wrinkle.
1. A pharmaceutical composition in the form of a gel comprising a human platelet lysate produced according to a method comprising (a) subjecting a population of human platelets to four freeze-thaw cycles, wherein the freeze portion of each cycle is carried out at a temperature lower than or equal to −190° C. and (b) mixing the platelet lysate with at least one pharmaceutically acceptable polymer and at least one pharmaceutically acceptable positively charged chemical species such that the resulting composition is an aqueous gel having a viscosity in the range of 1000 to 500,000 mPa·s (cps) at room temperature.