IP Library Granted Patent US 11,006,845
Granted Patent B2
US 11,006,845 · App. 16/316,403 · Granted May 18, 2021

System and method for measuring blood flow parameters in a blood vessel having an endovascular prosthesis

Inventors: David Kuraguntla (Bel Air, MD); Samit Kumar Gupta (Menlo Park, CA); Lilip Lau (Los Altos, CA); Anthony F. Flannery (Bainbridge Island, WA)
Assignee: Graftworx, Inc.
A61B5/0265A61B5/0031A61B5/026A61B5/6862A61F2/06A61F2/82A61F2/88A61F2250/0002
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Quick Facts
Patent No.
US 11,006,845
App. No.
16/316,403
Granted
May 18, 2021
Kind
B2
Abstract

Systems and methods for remotely monitoring blood flow that include an endovascular prosthesis. The endovascular prosthesis includes a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface. A monitoring device is disposed on the wall forming the lumen. The monitoring device comprises a sensor element configured to detect a physical event and to generate an electrical parameter shift in response to the physical event. An antenna portion is configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device. The second oscillating electrical signal is modulated by the electrical parameter shift.

Claims (24)

1. An endovascular prosthesis for implantation in a blood vessel comprising:

a conduit forming a lumen within a surrounding wall having an inner surface and an outer surface; and

a monitoring device disposed on the wall forming the lumen, the monitoring device comprising a sensor element configured to detect blood flow parameters in the blood vessel and generating an electrical parameter shift in response to the blood flow parameters, and an antenna portion configured to receive a first oscillating electrical signal from an interrogator device and to transmit a second oscillating electrical signal to the interrogator device where the second oscillating electrical signal is modulated by the electrical parameter shift;

at least one component of the monitoring device being integrated within a structure of the endovascular prosthesis, and wherein the sensor element is an integrated sensor element comprising a first metallic conduit, a second metallic conduit, and a sensor material, the sensor element forming at least a portion of a wire or strut element configured to form the wall structure of the endovascular prosthesis; and wherein the sensor element is formed as a coaxial capacitor, where the sensor material changes in capacitance when subject to pressure or stress, or the sensor element is formed as a variable resistor, where the sensor material is disposed between the first metallic conduit and the second metallic conduit and varies in resistance when subject to pressure or stress.

2. The endovascular prosthesis of claim 1 further comprising:

a sensor controlled oscillator configured to generate the second oscillating electrical signal where the electrical parameter shift of the sensor element determines a modulated frequency of the second oscillating electrical signal.

3. The endovascular prosthesis of claim 1 where the electrical parameter shift is in response to pressure or strain on the sensor element.

4. The endovascular prosthesis of claim 1 where the sensor controlled oscillator is a passive resonant circuit, where the electrical parameter shift by the sensor element in response to the blood flow parameters is a change in capacitance that varies the modulated frequency of the second oscillating electrical signal.

5. The endovascular prosthesis of claim 1 where the sensor controlled oscillator is a resistor controlled oscillator, where the electrical parameter shift by the sensor element in response to the blood flow parameters is a change in resistance that varies the modulated frequency of the second oscillating electrical signal.

6. The endovascular prosthesis of claim 1 where the sensor controlled oscillator is a voltage controlled oscillator, where electrical parameter shift by the sensor element in response to the blood flow parameters is a change in resistance that varies the modulated frequency at the output of the voltage controlled oscillator.

7. The endovascular prosthesis of claim 1 where the sensor element is any one of either a piezoresistive sensor, a piezoelectric strain gauge, or a variable capacitive sensor.

8. The endovascular prosthesis of claim 4 where the passive resonant circuit is a ring oscillator.

9. The endovascular prosthesis of claim 1 further comprising:

a passive power source configured to collect and store electrical energy from the first oscillating electrical signal.

10. The endovascular prosthesis of claim 1 further comprising a radio frequency identification detection mechanism configured to transmit an identifier of the device when energized by the first electrical oscillating signal.

11. The endovascular prosthesis of claim 1 where:

the wall of the endovascular prosthesis is formed by at least one of the following:

a plurality of coaxially disposed rings connected by at least one link;

a helix structure;

a braided structure;

a coil structure;

a structure of interconnected struts; and

the monitoring device is disposed on the wall of the endovascular prosthesis.

12. The endovascular prosthesis of claim 1 where at least a portion of the endovascular prosthesis is made of a metal, and at least a portion of the endovascular prosthesis made of metal is configured to operate as the antenna portion of the monitoring device.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2023
From: KURAGUNTLA, DAVID JOHN; GUPTA, SAMIT KUMAR; LAU, LILIP; FLANNERY, ANTHONY F.
To: GRAFTWORX, LLC
Reel/Frame 064406/0458 →
CHANGE OF NAME Recorded Jul 27, 2022
From: GRAFTWORX, INC.
To: ALIO, INC
Reel/Frame 060990/0555 →
Continuity (2)
Provisional Application 62361384 · Jul 12, 2016
Related Publication 20190246916A1 · Aug 15, 2019
Cited By (7)
US 12,268,493 US 12,310,707 US 12,465,233 US 12,465,324 US 12,539,212 US 12,672,848 US 12,721,590