Granted Patent B2

US 12,310,707 · App. 17/470,777 · Granted May 27, 2025

Inventors: Fiachra M. Sweeney (Dublin, IE); Hanson S. Gifford (Woodside, CA); Jessi Johnson (Sunnyvale, CA); Pablo Martin (Dublin, IE); Stephen Sheridan (County Cavan, IE); Douglas S. Sutton (Pacifica, CA); Friedrich Wetterling (Dublin, IE); Conor M. Hanley (Dublin, IE); Shriram Raghunathan (Menlo Park, CA); Sean Quinlan (Dublin, IE)

Assignee: Foundry Innovation & Research 1, Ltd.

A61B5/0265A61B5/0295A61B5/6862A61B5/076

Abstract

Claims (19)

1. An implantable vessel monitoring device configured and dimensioned to be implanted in a patient blood vessel in contact with the vessel wall, said device comprising:

a flexible sensor frame formed in an open center loop;

an expandable and collapsible variable inductance coil comprising a plurality of adjacent wire strands wrapped on the flexible sensor frame around the open center to allow substantially unimpeded blood flow therethrough, said coil configured and dimensioned (i) to extend around an inner periphery of the vessel when implanted therein and (ii) to move with the vessel wall in response to expansion and collapse of the vessel; and

a capacitance which together with said variable inductance coil forms a variable inductance resonant circuit having a variable characteristic frequency correlated to the diameter or area of the expandable and collapsible variable inductance coil;

wherein said plurality of wire strands are each individually insulated, and wherein said device is configured and dimensioned to be implanted within the patient's Inferior Vena Cava (IVC) in contact with the IVC wall; and

wherein said device is configured to exert a radial force in the range of about 0.05N-0.3N at 50% compression.

2. The implantable vessel monitoring device of claim 1 , wherein said expandable and collapsible variable inductance coil comprises plural wire strands arranged to extend around the open center in a lengthwise direction of the strands, and an inductance of the coil changes based on changes in cross-sectional area or diameter across the coil open center in response to expansion and collapse of said coil.

3. The implantable vessel monitoring device of claim 1 , wherein said capacitance consists essentially of an inherent capacitance produced by spaces between said adjacent wire strands.

4. The implantable vessel monitoring device of claim 1 , wherein said capacitance comprises a capacitor in electrical communication with said wire strands.

5. The implantable vessel monitoring device of claim 1 , wherein said device is configured to collapse with the IVC in an anterior-posterior direction from a generally circular cross-section to an oval or flattened cross-section without distortion of the vessel shape.

6. The implantable vessel monitoring device of claim 1 , wherein said plurality of wire strands and flexible sensor frame are covered together by an outer layer.

7. The implantable vessel monitoring device of claim 6 , wherein the plurality of wire strands fully surround the flexible sensor frame.

8. The implantable vessel monitoring device of claim 7 , wherein the flexible sensor frame is configured and dimensioned to form a loop surrounding an inner periphery of the vena cava when implanted therein, said loop being radially collapsible and expandable when implanted and having a combination of flexibility and stiffness selected to (i) support and maintain said variable inductance coil in contact with the vena cava wall, (ii) allow the vena cava to collapse and expand over the respiratory and cardiac cycles, and (iii) allow the variable inductance coil supported by said frame to change shape as a magnitude of collapse and expansion of the vena cava varies with vascular fluid volume of the patient.

9. The implantable vessel monitoring device of claim 1 , wherein said plurality of adjacent wire strands comprise plural side-by-side strands formed in at least one continuous loop around the open center.

10. The implantable vessel monitoring device of claim 9 , wherein said plurality of said plural side-by-side strands are in contact and electrically insulated from one another.

11. The implantable vessel monitoring device of claim 1 , wherein said expandable and collapsible coil is wrapped around the open center in a single bundle of multiple wire strands.

12. The implantable vessel monitoring device of claim 1 , wherein said expandable and collapsible coil is wrapped around the open center in multiple bundles of multiple wire strands.

13. The implantable vessel monitoring device of claim 1 , wherein said expandable and collapsible coil comprises 180 to 1000 individual wire strands.

14. The implantable vessel monitoring device of claim 1 , wherein each wire strand of said plurality of adjacent wire strands is in contact along a length direction with plural other strands of said plurality of adjacent wire strands.

Assignments (1)

Continuity (10)

References Cited (400)