IP Library › Granted Patent US 11,001,679
Granted Patent B2
US 11,001,679 · App. 16/358,299 · Granted May 11, 2021

Biofabricated material containing collagen fibrils

Inventors: Brendan Patrick Purcell (Brooklyn, NY); David Thomas Williamson (Landenberg, PA); Lixin Dai (Staten Island, NY); Darryl Miles Cassingham (Dorset, GB); Stephen M. Spinella (Brooklyn, NY)
Assignee: Modern Meadow, Inc.
C08J3/24B32B1/08B32B3/266B32B5/022B32B5/024B32B5/026B32B5/26B32B7/12B32B9/025B32B15/02B32B15/14B32B23/10B32B27/12B32B29/02C07K14/78C14C9/00C14C9/02C14C13/00D01C3/00D01F4/00D04H1/00D04H1/4382D04H13/00D06M15/05D06M15/15D06N3/00D06N3/0018D06N7/0097D06P3/32B32B2250/02B32B2250/03B32B2250/20B32B2250/40B32B2250/42B32B2255/02B32B2255/26B32B2262/0207B32B2262/0261B32B2262/0269B32B2262/0276B32B2262/0292B32B2262/04B32B2262/062B32B2262/065B32B2262/067B32B2262/08B32B2262/10B32B2262/101B32B2262/103B32B2262/106B32B2262/14B32B2264/105B32B2307/202B32B2307/208B32B2307/308B32B2307/4026B32B2307/422B32B2307/50B32B2307/51B32B2307/54B32B2307/5825B32B2307/708B32B2307/7265B32B2437/00B32B2437/02B32B2437/04B32B2439/46B32B2451/00B32B2457/00B32B2471/00B32B2479/00B32B2519/00B32B2571/00B32B2601/00B32B2605/003B32B2605/08B32B2605/12B32B2605/18C08J2389/06D06M23/16D06M2101/06D06N2201/06D06N2203/02
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Quick Facts
Patent No.
US 11,001,679
App. No.
16/358,299
Granted
May 11, 2021
Kind
B2
Abstract

A biofabricated material containing a network of crosslinked collagen fibrils is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).

Claims (8)

1. A biofabricated material

(i) comprising a network of non-human collagen fibrils,

wherein less than 10% by weight of the collagen fibrils in the material are in the form of collagen fibers having a diameter of 5 μm or more, are in the form of fibrils aligned for 100 μm or more of their lengths, or both;

wherein said material contains no more than 40% by weight water;

wherein said material contains at least 1% of a lubricant; or

(ii) comprising a network of recombinant non-human collagen fibrils, wherein the collagen contains substantially no 3-hydroxyproline;

wherein said material contains no more than 25% by weight water;

wherein said material contains at least 1% of a lubricant.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2020
From: PURCELL, BRENDAN PATRICK; WILLIAMSON, DAVID THOMAS; DAI, LIXIN; CASSINGHAM, DARRYL MILES; SPINELLA, STEPHEN M.
To: MODERN MEADOW, INC.
Reel/Frame 052176/0696 →
Continuity (3)
Continuation 15433777 · Feb 15, 2017
Provisional Application 62295435 · Feb 15, 2016
Related Publication 20190203000A1 · Jul 4, 2019
Cited By (2)
US 12,595,366 US 12,600,862