IP Library › Granted Patent US 10,946,185
Granted Patent B2
US 10,946,185 · App. 16/385,361 · Granted Mar 16, 2021

Topical neurological stimulation

Inventors: Graham H. Creasey (Menlo Park, CA); Hoo-Min D. Toong (Cambridge, MA)
Assignee: Neurostim Solutions, LLC
A61N1/0452A61N1/0456A61N1/0476A61N1/0492A61N1/36003A61N1/36007A61N1/36031A61N1/36034A61B5/04001A61B5/4836A61N1/36021
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Quick Facts
Patent No.
US 10,946,185
App. No.
16/385,361
Granted
Mar 16, 2021
Kind
B2
Abstract

A topical nerve stimulator patch and system are provided including a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.

Claims (30)

1. A topical nerve stimulation system for externally stimulating a nerve of a user, the system comprising:

a flexible substrate comprising adhesive on a first side adapted to adhere to a dermis of the user;

an electronic package directly coupled to the substrate, the electronic package comprising a control unit and one or more stimulators; and

electrodes directly coupled to the substrate and the electronic package and disposed between the adhesive and the dermis.

2. The topical nerve stimulation system of claim 1 , further comprising a power source coupled to the electronic package and an antenna coupled to the electronic package.

3. The topical nerve stimulation system of claim 1 , the electrodes comprising adhesive conductive pads.

4. The topical nerve stimulation system of claim 1 , the electronic package further comprising sensing circuits and an electronic switch to alternate between stimulating and sensing, the electrodes providing the stimulating and the sensing.

5. The topical nerve stimulation system of claim 1 , the substrate comprising a first end and a second end, a first electrode disposed on the first end and a second electrode disposed on the second end, the electronic package disposed between the first electrode and the second electrode.

6. The topical nerve stimulation system of claim 5 , the first electrode having a plurality of first electrode contacts and the second electrode having a plurality of second electrode contacts, the control unit adapted to apply an electrical signal to only the first electrode contacts or to both the first electrode contacts and the second electrode contacts simultaneously.

7. The topical nerve stimulation system of claim 1 , the electrodes comprising a plurality of electrode contacts in a concentric arrangement.

8. The topical nerve stimulation system of claim 1 , the electrodes comprising a plurality of electrode contacts arranged as parallel strips.

9. The topical nerve stimulation system of claim 1 , the electrodes comprising a plurality of electrode contacts arranged as a matrix.

10. The topical nerve stimulation system of claim 1 , the control unit adapted to apply an electrical signal via the stimulators to the electrodes to generate electrical stimuli of varying tissue depths based on a variation of power.

11. The topical nerve stimulation system of claim 1 , the electrodes comprising a pair of interlocking electrodes, the control unit adapted to apply a time-varying voltage signal via the stimulators to the interlocking electrodes to generate a beam forming electrical stimuli.

12. The topical nerve stimulation system of claim 1 , the control unit adapted to apply an electrical signal via the stimulators to the electrodes to cause an electrical stimuli to pass from the electrodes to the dermis.

13. The topical nerve stimulation system of claim 12 , the electrical stimuli comprising voltage-regulated square waves having frequencies between 15 Hz and 50 Hz, and having currents between 20 mA and 100 mA.

14. The topical nerve stimulation system of claim 1 , the electrodes comprising a beam forming array.

15. The topical nerve stimulation system of claim 2 , the antenna adapted to communicate with a remote control device configured to provide a signal to start or stop electrical stimuli via the electrodes.

16. A method for externally stimulating a nerve of a user, the method comprising:

fastening to the user a flexible substrate comprising adhesive on a first side adapted to adhere to a dermis of the user;

initiating electrical stimuli using an electronic package directly coupled to the substrate, the electronic package comprising a control unit and one or more stimulators; and

applying the electrical stimuli via electrodes directly coupled to the substrate and the electronic package and disposed between the adhesive and the dermis.

17. The method of claim 16 , the electrodes comprising a pair of interlocking electrodes, the control unit adapted to apply a time-varying voltage signal via the stimulators to the interlocking electrodes to generate a beam forming electrical stimuli.

18. The method of claim 16 , the electrodes comprising a beam forming array.

19. The method of claim 16 , the electronic package further comprising sensing circuits and an electronic switch, further comprising:

alternating between stimulating and sensing, the electrodes providing the stimulating and the sensing.

20. The method of claim 16 , the electrodes comprising a plurality of electrode contacts arranged as a matrix, further comprising:

the applying the electrical stimuli using a first pattern of the matrix;

sensing an activity of tissues within the user in response to the applying; and

re-applying the electrical stimuli using a second pattern of the matrix based on the sensing.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2019
From: CREASEY, GRAHAM HAROLD; TOONG, HOO-MIN D.
To: NEUROSTIM SOLUTIONS LLC
Reel/Frame 050469/0111 →
Continuity (4)
Continuation 15650228 · Jul 14, 2017
Division 14893946
Provisional Application 61828981 · May 30, 2013
Related Publication 20190240485A1 · Aug 8, 2019
Cited By (1)
US 12,465,776