IP Library Granted Patent US 11,241,433
Granted Patent B2
US 11,241,433 · App. 16/449,758 · Granted Feb 8, 2022

Treatment or prevention of autism disorders using menthol, linalool and/or icilin

Inventors: Susana Camacho (Lausanne, CH); Stephanie Michlig Gonzalez (Le Mont-sur-Lausanne, CH); Johannes Le Coutre (Pully, CH); Henry Markram (Lausanne, CH); Maurizio Pezzoli (Lausnne, CH)
Assignee: Societe des Produits Nestle S.A.
A61K31/513A23L33/105A61K9/0053A61K31/045A23V2002/00
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Quick Facts
Patent No.
US 11,241,433
App. No.
16/449,758
Granted
Feb 8, 2022
Kind
B2
Abstract

Compositions for treatment or prevention of autism disorders are provided, and the compositions contain a therapeutically effective amount of a compound selected from the group consisting of Menthol, Linalool, Icilin and combinations thereof. Methods for treatment or prevention of autism disorders are also provided, and the methods include administering such compositions.

Claims (7)

1. A method for treating an autism disorder, the method comprising administering to an individual having the autism disorder a composition comprising a therapeutically effective amount of a compound selected from the group consisting of Linalool, Icilin and combinations thereof, the composition is administered in a daily amount that comprises 10.0 mg of the compound/kg of body weight of the individual to 100 mg of the compound/kg of body weight of the individual.

2. The method of claim 1 wherein the autism disorder is selected from the group consisting of classic autism, Asperger's syndrome, childhood disintegrative disorder, Rett syndrome, pervasive developmental disorders-not otherwise specified, fragile X syndrome, and combinations thereof.

3. The method of claim 1 wherein the composition is selected from the group consisting of a medicament, a food product and a supplement to a food product.

4. The method of claim 1 wherein the composition is administered periodically for at least one year.

5. The method of claim 1 , wherein the composition is a food product.

6. The method of claim 5 , wherein the food product comprises a component selected from the group consisting of protein, carbohydrate, fat and combinations thereof.

7. The method of claim 1 wherein the composition does not contain glutamate antagonists.

Assignments (2)
MERGER Recorded Oct 30, 2019
From: NESTEC S.A.
To: SOCIETE DES PRODUITS NESTLE S.A.
Reel/Frame 050866/0265 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 30, 2019
From: CAMACHO, SUSANA; GONZALEZ, STEPHANIE MICHLIG; LE COUTRE, JOHANNES; MARKRAM, HENRY
To: NESTEC S.A.
Reel/Frame 050877/0036 →
Continuity (3)
Division 14892038
Provisional Application 61827229 · May 24, 2013
Related Publication 20190307748A1 · Oct 10, 2019