IP Library Granted Patent US 10,898,732
Granted Patent B2
US 10,898,732 · App. 16/538,648 · Granted Jan 26, 2021

Multi-color charged particle detector apparatus and method of use thereof

Inventors: Maureen Petterson (Somerville, MA); W. Davis Lee (Rockport, ME)
A61N5/1077A61B6/03A61N5/1044A61N5/1067A61N5/1082G21K1/087G21K1/093G21K5/04A61N5/107A61N2005/1074A61N2005/1087A61N2005/1097H01J35/14
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Quick Facts
Patent No.
US 10,898,732
App. No.
16/538,648
Granted
Jan 26, 2021
Kind
B2
Abstract

The invention comprises a method and apparatus for using a multi-layer multi-color scintillation based detector element to image a tumor of a patient using a process of determining residual energies of positively charged particles after passing through the patient, the process comprising the steps of: (1) transmitting the positively charged particles at known energies through the patient and into a multi-layer detector element; (2) detecting first and second secondary photons, resultant from passage of the positively charged particles, respectively from a first layer of a first scintillation material and a second layer of a second scintillation material at two respective layer depths, where the first wavelength range differs from the second wavelength range; (4) determining residual energies of the positively charged particles, using output from the step of detecting; and (5) relating the residual energies to body densities to generate an image.

Claims (11)

1. A method for determining residual energy of positively charged particles after passing through a patient, comprising the steps of:

passing the positively charged particles into a multi-layer detector element;

detecting first secondary photons, resultant from passage of the positively charged particles, over a first wavelength range from a first layer of said multi-layer detector, said first layer comprising a first scintillation material;

detecting second secondary photons, resultant from passage of the positively charged particles, over a second wavelength range from a second layer of said multi-layer detector element, the first wavelength range differing from the second wavelength range; and

determining, from a set of response signals generated from depths into said multi-layer detector element prior to a Bragg peak termination point of the first scintillation material, a depth of penetration of the positively charged particles into said multi-layer detector element.

2. A method for determining residual energy of positively charged particles after passing through a patient, comprising the steps of:

passing the positively charged particles into a multi-layer detector element;

detecting first secondary photons, resultant from passage of the positively charged particles, over a first wavelength range from a first layer of said multi-layer detector, said first layer comprising a first scintillation material;

detecting second secondary photons, resultant from passage of the positively charged particles, over a second wavelength range from a second layer of said multi-layer detector element, the first wavelength range differing from the second wavelength range;

transmitting the positively charged particles entirely through a backside of said multi-layer detection element relative to the patient; and

determining an initial energy of the positively charged particles entering said multi-layer detection element from a response curve of said first secondary photons and said second secondary photons as a function of depth in said multi-layer detector element.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2023
From: PETTERSON, MAUREEN; LEE, W DAVIS
To: PROTOM INTERNATIONAL HOLDING CORPORATION
Reel/Frame 062383/0674 →
Continuity (14)
Continuation In Part 15901770 · Feb 21, 2018
Continuation In Part 15892240 · Feb 8, 2018
Continuation In Part 15838072 · Dec 11, 2017
Continuation In Part 15823148 · Nov 27, 2017
Continuation In Part 15467840 · Mar 23, 2017
Continuation In Part 15402739 · Jan 10, 2017
Continuation In Part 15348625 · Nov 10, 2016
Continuation In Part 15167617 · May 27, 2016
Continuation In Part 15868897 · Jan 11, 2018
Continuation 15152479 · May 11, 2016
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13087096 · Apr 14, 2011
Provisional Application 61324776 · Apr 16, 2010
Related Publication 20190366125A1 · Dec 5, 2019
Cited By (1)
US 12,245,355