IP Library Granted Patent US 11,305,132
Granted Patent B2
US 11,305,132 · App. 16/582,426 · Granted Apr 19, 2022

System for non-invasive heart treatment

Inventors: Michail Pankratov (Waltham, MA); Federico Benetti (Rosario, AR); Judie Vivian (Huntington Beach, CA)
Assignee: Varian Medical Systems, Inc.
A61N5/10A61N5/1039A61N5/1049A61N5/1084A61N5/1064
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,305,132
App. No.
16/582,426
Granted
Apr 19, 2022
Kind
B2
Abstract

The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.

Claims (27)

1. A noninvasive system for imaging and treating cardiac arrhythmia in a subject, the system comprising:

a scanning component, wherein the scanning component generates an image of one or more target regions of the heart;

a treatment planning workstation, wherein the treatment planning workstation is configured to prescribe a treatment;

a source of particle beam radiation or x-ray radiation; and

a robotic system comprising a computer processor that is configured to direct radiation from outside the patient toward the one or more target regions of the heart.

2. The noninvasive system of claim 1 , wherein the treatment comprises a legion pattern.

3. The noninvasive system of claim 1 , wherein the source of particle beam radiation or x-ray radiation is mounted to a robotic arm of the robotic system.

4. The noninvasive system of claim 1 , wherein the treatment comprises one or more doses of radiation.

5. The noninvasive system of claim 1 , wherein the treatment comprises more than 50 doses of radiation.

6. The noninvasive system of claim 1 , wherein the treatment comprises an outpatient procedure.

7. The noninvasive system of claim 1 , wherein the treatment comprises a plurality of doses of radiation delivered from different directions relative to the heart.

8. The noninvasive system of claim 1 , wherein the robotic system is configured to adjust a direction of the radiation based on movement of the one or more target regions of the heart.

9. The noninvasive system of claim 1 , wherein the movement of the one more target regions of the heart is caused by patient breathing.

10. The noninvasive system of claim 1 , wherein the movement of the one or more target regions of the heart is caused by blood flow.

11. A method of treating cardiac arrhythmia comprising:

determining a lesion pattern to treat the cardiac arrhythmia;

determining one or more target treatment regions in the heart based on the lesion pattern; and

directing a radiation-based non-invasive therapy to the one or more target treatment regions in the heart.

12. The method of claim 11 , wherein the step of directing a radiation-based non-invasive therapy results in the formation of at least one lesion in the heart.

13. The method of claim 11 , wherein the step of directing a radiation-based non-invasive therapy comprises directing radiation from outside the patient.

14. The method of claim 11 , wherein the step of directing a radiation-based non-invasive therapy comprises delivering a predetermined dose of radiation.

15. The method of claim 14 , wherein the predetermined dose of radiation is repeated at least twice during a treatment session.

16. The method of claim 14 , wherein the predetermined dose of radiation is repeated at least twice during a treatment session.

17. The method of claim 11 , wherein the step of directing a radiation-based non-invasive therapy comprises delivering a plurality of doses of radiation from outside the patient.

18. The method of claim 17 , wherein each dose of radiation in the plurality of doses of radiation are delivered from different positions relative to the heart.

19. The method of claim 11 , wherein the radiation-based non-invasive therapy is performed by a linear accelerator mounted to a robotic arm.

20. The method of claim 11 , wherein the step of determining one or more target treatment regions in the heart is performed using a treatment planning workstation.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2022
From: PANKRATOV, MICHAIL; BENETTI, FEDERICO; VIVIAN, JUDIE
To: CYBERHEART, INC.
Reel/Frame 059225/0476 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2022
From: CYBERHEART, INC.
To: VARIAN MEDICAL SYSTEMS, INC.
Reel/Frame 059359/0776 →
Continuity (8)
Continuation 15881517 · Jan 26, 2018
Continuation 14189668 · Feb 25, 2014
Continuation 12637458 · Dec 14, 2009
Continuation 11080318 · Mar 14, 2005
Continuation 10651764 · Aug 29, 2003
Provisional Application 60438876 · Jan 8, 2003
Provisional Application 60445716 · Feb 7, 2003
Related Publication 20200108274A1 · Apr 9, 2020