IP Library Granted Patent US 11,179,382
Granted Patent B2
US 11,179,382 · App. 16/680,677 · Granted Nov 23, 2021

Methods of reversing normal aging process and extending lifespan

Inventor: Jonnie R. Williams (Sarasota, FL)
Assignee: MyMD Pharmaceuticals (Florida), Inc.
A61K31/465A61K8/4926A61K31/4439A61P3/08C07K14/4747Y02A50/30
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Quick Facts
Patent No.
US 11,179,382
App. No.
16/680,677
Granted
Nov 23, 2021
Kind
B2
Abstract

In one aspect, a method of altering programmed cell death includes administering to an individual in need thereof a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In other aspects, isomyosmine is administered to treat a wound, hemochromatosis, traumatic brain injury, or disorders associated with chronic oxidative stress. In other aspects, isomyosmine is administered to increase blood oxygen saturation levels.

Claims (10)

1. A method of extending lifespan of an individual comprising administering to the individual a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the therapeutically effective amount is from about 0.01 to about 75 mg/kg/day.

3. The method of claim 1 , wherein the therapeutically effective amount is from about 0.1 to about 50 mg/kg/day.

4. The method of claim 1 , wherein the therapeutically effective amount is from about 1 to about 25 mg/kg/day.

5. The method of claim 1 , wherein the therapeutically effective amount is from about 5 to about 15 mg/kg/day.

6. A method of altering programmed cell death comprising administering to an individual a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof, wherein altering programmed cell death is effective to extend lifespan of the individual.

7. The method of claim 6 , wherein the therapeutically effective amount is from about 0.01 to about 75 mg/kg/day.

8. The method of claim 6 , wherein the therapeutically effective amount is from about 0.1 to about 50 mg/kg/day.

9. The method of claim 6 , wherein the therapeutically effective amount is from about 1 to about 25 mg/kg/day.

10. The method of claim 6 , wherein the therapeutically effective amount is from about 5 to about 15 mg/kg/day.

Assignments (4)
CHANGE OF NAME Recorded Jun 10, 2025
From: MYMD PHARMACEUTICALS, INC.
To: TNF PHARMACEUTICALS, INC.
Reel/Frame 071501/0834 →
MERGER Recorded Apr 22, 2022
From: MYMD PHARMACEUTICALS (FLORIDA), INC.
To: MYMD PHARMACEUTICALS, INC.
Reel/Frame 059680/0941 →
CHANGE OF NAME Recorded Jun 25, 2021
From: MYMD PHARMACEUTICALS, INC.
To: MYMD PHARMACEUTICALS (FLORIDA), INC.
Reel/Frame 056670/0396 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 13, 2019
From: WILLIAMS, JONNIE R.
To: MYMD PHARMACEUTICALS, INC.
Reel/Frame 050998/0235 →
Continuity (4)
Continuation 15719875 · Sep 29, 2017
Continuation In Part PCTUS2016025126 · Mar 31, 2016
Provisional Application 62140618 · Mar 31, 2015
Related Publication 20200078344A1 · Mar 12, 2020