Methods and devices for skin tightening
The present invention relates to methods and devices for skin tightening after incising or excising tissue portions from a subject. Exemplary methods and devices include tunable dressings having an adhesive layer and a regulatable layer or an un-stretched layer that responds to one or more external stimuli to contract or expand the dressing, where the contraction or expansion can be uniform or non-uniform.
1. A system for skin tightening comprising:
a tube configured to contact a surface of skin to generate holes in skin tissue by excising portions of the skin tissue;
a first actuator configured to rotate the tube relative to the skin;
a suction or pressure system to facilitate removal of skin portions from the tube;
a stop arrangement to control the depth of the excision and/or the length of excised tissue portions, wherein the stop arrangement is adjustable along a long axis of the tube to control the depth of excision in the skin; and
a device affixable to a skin region comprising a plurality of the excised tissue portions, wherein said device provides contraction or expansion of said skin region in one or more directions.
2. The system of claim 1 , wherein the first actuator is configured to translate the tube relative to the skin.
3. The system of claim 1 , comprising a second actuator configured to translate the tube relative to the skin.
4. The system of claim 1 , wherein at least one of said plurality of said excised tissue portions has a length of more than 1 mm.
5. The system of claim 1 , wherein at least one of said plurality of said excised tissue portions has a length of about 3.5 mm.
6. The system of claim 1 , wherein an areal fraction of excised tissue portions is less than about 70% of the skin region.
7. The system of claim 1 , wherein an areal fraction of excised tissue portions is less than about 10% of the skin region.
8. The system of claim 1 , wherein said plurality of excised tissue portions comprise one or more elliptical holes in said skin region.
9. The system of claim 1 , wherein the device is or comprises a dressing.
10. The system of claim 1 , wherein the device comprises an adhesive material.
11. The system of claim 1 , wherein the device comprises an unstretched material.
12. The system of claim 1 , wherein the device comprises one or more shape memory polymer fibers or wires, and wherein contraction of said skin region is provided by aligning the one or more shape memory polymer fibers or wires along one or more directions.
13. The system of claim 1 , wherein the skin region is located on a face, eyelid, cheek, chin, forehead, lips, nose, neck, chest, arm, leg, and/or a back.