Compositions and methods for the treatment of presbyopia
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
1. A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent.
2. A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent and a viscosity agent.
3. A method of treating presbyopia comprising administering a composition comprising aceclidine as the only active agent and one or more nonionic surfactants to a subject in need thereof.
4. The method of claim 3 , wherein aceclidine is at a concentration from about 0.25% to about 2.5% w/v, wherein w/v denotes weight by total volume of the composition.
5. The method of claim 3 , wherein aceclidine is at a concentration from about 0.75% to about 2.5% w/v.
6. A method of treating low regular astigmatism, low or high irregular astigmatism, keratoconic ectasia, night vision halos/starbursts, night vision reduced contrast, and low myopia, or hyperopia, with or without astigmatism, comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine as the only active agent and a viscosity agent.