Phenothiazine diaminium salts and their use

Inventors: Colin Marshall (Old Aberdeen, GB); Scott Clunas (Old Aberdeen, GB); John Mervyn David Storey (Aberdeen, GB); James Peter Sinclair (Old Aberdeen, GB); Thomas Craven Baddeley (Old Aberdeen, GB); Ahtsham Ishaq (Old Aberdeen, GB); Michael Simpson (Old Aberdeen, GB); Craig Williamson (Guildford, GB); Barry Alan Wood (Old Aberdeen, GB); Claude Michel Wischik (Aberdeen, GB); Charles Robert Harrington (Aberdeen, GB); Janet Elizabeth Rickard (Aberdeen, GB); David Horsley (Aberdeen, GB); Yin Sze Loh (Singapore, SG); Karrar Ahmad Khan (West Bridgeford, GB); Christopher Paul Larch (Old Aberdeen, GB)

Assignee: WisTa Laboratories Ltd.

C07D279/20 A61K9/0053 A61K9/2095 A61K31/5415 A61L2/0052 A61P31/04 A61P31/12 A61P31/14 A61P31/18 A61P33/02 A61P33/06 A61P35/00 A61K9/2893 C07C303/32 C07C309/04 C07C309/05 C07C309/30 C07C309/35 Y02A50/30

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Quick Facts

Patent No.: US 11,180,464
App. No.: 16/751,811
Granted: Nov 23, 2021
Kind: B2

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Abstract

Disclosed are compounds of general formula (I): and pharmaceutically acceptable salts thereof, formulations, methods and uses in, for example, the treatment of disease.

Claims (3)

1. A compound of the following formula:

or a pharmaceutically acceptable salt, solvate, or hydrate thereof.

2. The compound according to claim 1 in crystalline form, having a crystal structure as represented by FIGS. 11-16 .

Assignments (4)

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 2, 2021

From: MARSHALL, COLIN; CLUNAS, SCOTT; STOREY, JOHN MERVYN DAVID; SINCLAIR, JAMES PETER; BADDELEY, THOMAS CRAVEN; ISHAQ, AHTSHAM; SIMPSON, MICHAEL; WILLIAMSON, CRAIG; WOOD, BARRY ALAN; WISCHIK, CLAUDE MICHEL; HARRINGTON, CHARLES ROBERT; RICKARD, JANET ELIZABETH; HORSLEY, DAVID

To: WISTA LABORATORIES LTD.

Reel/Frame 056741/0177 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 2, 2021

From: LOH, YIN SZE

To: WISTA LABORATORIES LTD.

Reel/Frame 056741/0275 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 2, 2021

From: KHAN, KARRAR AHMAD

To: WISTA LABORATORIES LTD.

Reel/Frame 056741/0311 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2021

From: LARCH, CHRISTOPHER PAUL