Granted Patent
B2
US 11,084,804 · App. 16/789,945 · Granted Aug 10, 2021
Modulators of ATP-binding cassette transporters
Inventors:
Sara S. Hadida Ruah (La Jolla, CA); Matthew M. Hamilton (Hackettstown, NJ); Mark Miller (San Diego, CA); Peter D. J. Grootenhuis (San Diego, CA)
Assignee:
Vertex Pharmaceuticals Incorporated
C07D405/12A61K31/443A61K31/444A61K31/4545A61K31/47A61K31/4709A61K31/496A61K31/497A61K31/501A61K31/506A61K31/5377A61K45/06C07D317/12C07D405/14
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Abstract
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Claims (1)
1. A compound having the following chemical structure:
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 13, 2020
From: HADIDA RUAH, SARA; HAMILTON, MATTHEW; MILLER, MARK; GROOTENHUIS, PETER; BEAR, BRIAN; MCCARTNEY, JASON; ZHOU, JINGLAN; VAN GOOR, FREDRICK
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 051813/0260 →
CHANGE OF ADDRESS
Recorded Feb 13, 2020
From: VERTEX PHARMACEUTICALS INCORPORATED
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 051929/0224 →
Continuity (10)
Continuation
14994487
· Jan 13, 2016
Continuation
PCTUS2006043289
· Nov 8, 2006
Provisional Application
60802458
· May 22, 2006
Provisional Application
60754086
· Dec 27, 2005
Provisional Application
60734506
· Nov 8, 2005