Method of treating coronavirus
In one aspect, a coronavirus is treated by administering a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In another aspect, oxidative stress is reduced in an individual suffering from a coronavirus by administering a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In another aspect, mitochondrial reactive oxygen species (mtROS) are inhibited in an individual suffering from a coronavirus by administering a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In one example, the coronavirus is Covid-19.
1. A method of modulating an anti-inflammatory counteractive response characterized by release of cytokines in an individual suffering from a viral infection, the method comprising administering to the individual a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle therefor.
2. The method of claim 1 , wherein the viral infection is Th1-mediated, and the anti-inflammatory counteractive response is characterized by release of Th-2-type cytokines.
3. The method of claim 2 , wherein a virus causing the Th1-mediated viral infection causes a respiratory disorder.
4. The method of claim 1 , wherein the therapeutically effective amount is from about 0.01 to about 50 mg/kg/day.
5. The method of claim 1 , wherein the therapeutically effective amount is from about 0.1 to about 25 mg/kg/day.
6. The method of claim 1 , wherein the therapeutically effective amount is from about 1 to about 10 mg/kg/day.
7. The method of claim 1 , wherein the pharmaceutically acceptable salt is isomyosmine hydrochloride.