Granted Patent
B2
US 11,035,867 · App. 16/851,690 · Granted Jun 15, 2021
Use and treatment of di-amino acid repeat-containing proteins associated with ALS
View Patent ↗
Loading inventors, assignments & file history…
Abstract
Disclosed herein are methods and compositions for identifying and/or treating subjects having or likely to have amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD). Antibodies specific for one or more di-amino acid repeat-containing proteins are also provided herein.
Claims (3)
1. A method of producing an antibody, the method comprising administering to a subject a di-amino acid repeat-containing protein antigen consisting of a poly-(Gly-Pro) di-amino acid repeat peptide.
2. The method of claim 1 , wherein the di-amino acid repeat-containing protein antigen comprises the sequence set forth in SEQ ID NO: 21.
3. The method of claim 1 , further comprising the step of isolating the antibody from the subject.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 2, 2020
From: RANUM, LAURA; ZU, TAO
To: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
Reel/Frame 053105/0732 →
Continuity (5)
Division
14775278
Provisional Application
61883219
· Sep 27, 2013
Provisional Application
61786258
· Mar 14, 2013