IP Library Granted Patent US 11,453,694
Granted Patent B2
US 11,453,694 · App. 16/878,911 · Granted Sep 27, 2022

Glycosyl hesperetin and process for producing the same and uses thereof

Inventors: Mitsuyuki Kambe (Okayama, JP); Koichi Nishi (Okayama, JP); Akira Kawashima (Okayama, JP); Akiko Yasuda (Okayama, JP); Hitoshi Mitsuzumi (Okayama, JP); Toshio Ariyasu (Okayama, JP)
Assignee: HAYASHIBARA CO. LTD.
C07H17/07A23L2/52A23L27/2052A23L27/84A23L33/10A23L33/15A61K8/602A61K31/7048A61Q19/00C12P19/14C12P19/18C12P19/60A23V2002/00A61K2800/10
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Quick Facts
Patent No.
US 11,453,694
App. No.
16/878,911
Granted
Sep 27, 2022
Kind
B2
Abstract

The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.

Claims (9)

1. A glycosyl hesperetin composition, which comprises as glycosyl hesperetin α-glycosyl hesperidin and either or both of hesperidin and 7-O-β-glucosyl hesperetin in an amount of 90% by mass or more but less than 100% by mass, on a dry solid basis, wherein the content of furfural measured on GC/MS analysis is less than 200 ppb, on a dry solid basis.

2. The glycosyl hesperetin composition of claim 1 , wherein the content of 4-methoxystylene measured on GC/MS analysis is less than 30 ppb, on a dry solid basis.

3. The glycosyl hesperetin composition of claim 1 , wherein the content of α-glycosyl hesperidin is 50% by mass or more but less than 100% by mass, on a dry solid basis.

4. The glycosyl hesperetin composition of claim 1 , wherein said α-glycosyl hesperidin is α-glucosyl hesperidin.

5. The glycosyl hesperetin composition of claim 4 , wherein the content of α-glucosyl hesperidin is 60% by mass or more but 90% by mass or lower, on a dry solid basis.

6. A method for reducing the miscellaneous tastes of a glycosyl hesperetin composition comprising as glycosyl hesperetin α-glycosyl hesperidin and either or both of hesperidin and 7-O-β-glucosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, said method comprising a step of contacting said glycosyl hesperetin composition with an inorganic reducing agent to reduce the miscellaneous tastes.

7. The method of claim 6 , wherein the content of α-glycosyl hesperidin is 50% by mass or more but less than 100% by mass to said glycosyl hesperetin, on a dry solid basis.

8. The method of claim 6 , wherein said α-glycosyl hesperidin is α-glucosyl hesperidin.

9. The method of claim 6 , wherein said inorganic reducing agent is a sulfite.

Assignments (2)
CHANGE OF NAME Recorded Mar 18, 2025
From: HAYASHIBARA CO., LTD.
To: NAGASE VIITA CO., LTD.
Reel/Frame 070538/0828 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 20, 2020
From: KAMBE, MITSUYUKI; NISHI, KOICHI; KAWASHIMA, AKIRA; YASUDA, AKIKO; MITSUZUMI, HITOSHI; ARIYASU, TOSHIO
To: HAYASHIBARA CO. LTD.
Reel/Frame 052712/0392 →
Priority Claims (2)
JP 2014-041066 · Mar 3, 2014 · national
JP 2014-266504 · Dec 26, 2014 · national
Continuity (2)
Division 15122708
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