IP Library › Granted Patent US 11,446,483
Granted Patent B2
US 11,446,483 · App. 16/918,134 · Granted Sep 20, 2022

Patterned stimulation intensity for neural stimulation

Inventors: Dustin Tyler (Highland Heights, OH); Daniel Tan (Cleveland, OH); Matthew Schiefer (Shaker Heights, OH)
Assignee: CASE WESTERN RESERVE UNIVERSITY
A61N1/0551A61N1/361A61N1/36003A61N1/36014A61N1/3615A61N1/36031A61N1/36034A61N1/36067A61N1/36103A61N1/36139A61N1/36146A61N1/36178A61N1/36189
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Quick Facts
Patent No.
US 11,446,483
App. No.
16/918,134
Granted
Sep 20, 2022
Kind
B2
Abstract

One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.

Claims (25)

1. A method comprising:

receiving a signal in response to a device performing an action, wherein the device is at a location remote from a user, wherein the signal comprises a trigger for a virtual sensation, and wherein the virtual sensation connects one or more nerves of the user to the action of the device;

configuring a stimulation signal with a pattern of stimulation intensities based on the trigger for the virtual sensation; and

delivering the stimulation signal to one or more nerves to cause the virtual sensation.

2. The method of claim 1 , wherein the one or more nerves comprise sensory fibers and/or autonomic fibers.

3. The method of claim 2 , wherein the stimulation signal is configured to activate at least a portion of the sensory fibers and/or the autonomic fibers.

4. The method of claim 1 , wherein the action is a mechanical action.

5. The method of claim 4 , wherein the virtual sensation connects the one or more nerves to the mechanical action of the device in response to the mechanical action.

6. The method of claim 1 , wherein the virtual sensation is translated and/or scaled from the signal.

7. The method of claim 6 , wherein the signal is physiologically unsafe, but the virtual sensation is physiologically safe.

8. The method of claim 1 , wherein the device is located in a healthcare setting.

9. The method of claim 8 , wherein the virtual sensation enables a clinician to perform a procedure on a patient at a remote location.

10. The method of claim 8 , wherein the virtual sensation enables a person to visit a patient at a remote location.

11. A system comprising:

a pulse generator configured to:

receive a signal in response to a device performing an action, wherein the device is at a location remote from a user, wherein the signal comprises a trigger for a virtual sensation; and

configure a stimulation signal with a pattern of stimulation intensities based on the trigger for the virtual sensation; and

at least one electrode configured to deliver the stimulation signal to one or more nerves of the user to cause the virtual sensation, wherein the virtual sensation connects the one or more nerves to the action of the device.

12. The system of claim 11 , wherein the one or more electrodes comprise cuff electrodes configured to at least partially surround the one or more nerves.

13. The system of claim 11 , wherein the action is a mechanical action.

14. The system of claim 11 , wherein the device is located in a healthcare setting.

15. The system of claim 14 , wherein the virtual sensation enables a clinician to perform a procedure on a patient at a remote location.

16. The system of claim 14 , wherein the virtual sensation enables a person to visit a patient at a remote location.

17. The system of claim 11 , wherein the stimulation signal is configured to activate at least a portion of sensory fibers and/or autonomic fibers within the one or more nerves.

18. The system of claim 11 , wherein the signal is physiologically unsafe, but the virtual sensation is physiologically safe and translated and/or scaled from the signal.

Continuity (4)
Continuation 16175967 · Oct 31, 2018
Continuation 15104589
Continuation PCTUS2013075329 · Dec 16, 2013
Related Publication 20200330751A1 · Oct 22, 2020