IP Library Granted Patent US 11,001,595
Granted Patent B2
US 11,001,595 · App. 16/947,650 · Granted May 11, 2021

Pyrimidine compounds and pyrimido indole compounds and methods of use

Inventor: Aleem Gangjee (Allison Park, PA)
Assignee: Duquesne University of The Holy Spirit
C07D495/04A61K31/343A61K31/4709A61K31/505C07D239/48C07D403/02C07D405/02C07D487/04
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Quick Facts
Patent No.
US 11,001,595
App. No.
16/947,650
Granted
May 11, 2021
Kind
B2
Abstract

The present invention discloses a compound of the formula: wherein R is hydrogen or an alkyl group having from one to ten carbon atoms, or a compound of the formula wherein the S is replaced by CH 2 or O, and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt or hydrate thereof.

Claims (9)

1. A compound of the formula:

wherein R is an alkyl group having from seven to ten carbon atoms, or a pharmaceutically acceptable salt or hydrate thereof.

2. A compound of the formula:

wherein R is an alkyl group having from seven to ten carbon atoms, or a pharmaceutically acceptable salt or hydrate thereof.

3. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula:

wherein R is an alkyl group having from seven to ten carbon atoms, or a pharmaceutically acceptable salt or hydrate thereof.

4. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula:

wherein R is an alkyl group having from ene seven to ten carbon atoms, or a pharmaceutically acceptable salt or hydrate thereof.

5. The pharmaceutical composition of any one of claims 3 or 4 comprising at least one pharmaceutical carrier.

Assignments (2)
CONFIRMATORY LICENSE Recorded Oct 13, 2023
From: DUQUESNE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 065238/0077 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 8, 2021
From: GANGJEE, ALEEM
To: DUQUESNE UNIVERSITY OF THE HOLY SPIRIT
Reel/Frame 055861/0490 →
Continuity (5)
Division 16253751 · Jan 22, 2019
Division 15479752 · Apr 5, 2017
Division 14820725 · Aug 7, 2015
Provisional Application 62035234 · Aug 8, 2014
Related Publication 20200369680A1 · Nov 26, 2020