IP Library Granted Patent US 11,111,252
Granted Patent B2
US 11,111,252 · App. 16/947,651 · Granted Sep 7, 2021

Pyrimidine compounds and pyrimido indole compounds and methods of use

Inventor: Aleem Gangjee (Allison Park, PA)
Assignee: Duquesne University of The Holy Spirit
C07D495/04A61K31/343A61K31/4709A61K31/505C07D239/48C07D403/02C07D405/02C07D487/04
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Quick Facts
Patent No.
US 11,111,252
App. No.
16/947,651
Granted
Sep 7, 2021
Kind
B2
Abstract

The present invention discloses a compound of the formula: and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt or hydrate thereof.

Claims (5)

1. A compound of the formula:

wherein R is 2-OCH 3 , 3-OCH 3 , 4-OCH 3 , or 3,4-diOCH 3 , or a pharmaceutically acceptable salt or hydrate thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula:

wherein R is 2-OCH 3 , 3-OCH 3 , 4-OCH 3 , or 3,4-diOCH 3 , and optionally comprising a pharmaceutically acceptable salt or hydrate thereof.

3. The pharmaceutical composition of claim 1 comprising at least one pharmaceutical carrier.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 6, 2021
From: GANGJEE, ALEEM
To: DUQUESNE UNIVERSITY OF THE HOLY SPIRIT
Reel/Frame 056762/0460 →
Continuity (5)
Division 16253751 · Jan 22, 2019
Division 15479752 · Apr 5, 2017
Division 14820725 · Aug 7, 2015
Provisional Application 62035234 · Aug 8, 2014
Related Publication 20200369681A1 · Nov 26, 2020