IP Library Granted Patent US 11,446,086
Granted Patent B2
US 11,446,086 · App. 17/013,082 · Granted Sep 20, 2022

Picosecond optical radiation systems and methods of use

Inventors: Mirko Georgiev Mirkov (Chelmsford, MA); Daniel Hohm (Merrimac, NH); Christian Hoffman (Hopedale, MA); Rafael Armando Sierra (Palmer, MA)
Assignee: CYNOSURE, LLC
A61B18/203A61N5/0616H01S3/0627H01S3/08018H01S3/094076H01S3/1024H01S3/1106H01S3/1109H01S3/1121A61B2018/0047A61N5/067H01S3/0092H01S3/08054H01S3/093H01S3/094038H01S3/094084H01S3/107H01S3/1611H01S3/1623H01S3/1633H01S3/1643H01S3/1673
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Quick Facts
Patent No.
US 11,446,086
App. No.
17/013,082
Granted
Sep 20, 2022
Kind
B2
Abstract

Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a losing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.

Claims (32)

1. A method for treating pigment particles, the method comprising:

providing a picosecond pulse radiation source comprising a mode locked laser, wherein the mode locked laser is a multi transverse mode laser comprising,

a solid state crystal medium;

a resonator defined by a first mirror and a second mirror at opposite ends of a resonator optical axis, the solid state crystal medium disposed therein;

a fundamental frequency which is the speed of light divided by a round trip optical path length (2 L) of the resonator;

a mode locking element that is modulated at a frequency that is a sub-harmonic (l/n) of the fundamental frequency, which is the speed of light divided by round trip optical path length (2L) where n is a whole number greater than 1;

generating a pulse of optical radiation, using the pulse radiation source, wherein the pulse has a duration of less than 1000 picoseconds; and

directing the pulse to one or more pigment particle target to disrupt the one or more pigment particle target and promote clearance thereof.

2. The method of claim 1 wherein an output energy pulse from the resonator is at least a 100 mJ/pulse.

3. The method of claim 1 wherein directing the pulse further comprises directing the pulse from the pulse radiation source through a treatment beam delivery system to one or more pigment particle target to disrupt the one or more pigment particle target and promote clearance thereof.

4. The method of claim 3 , wherein the treatment beam delivery system is operable to apply a treatment beam to tissue comprising a tattoo, a pigmented lesion, or a skin disorder, wherein the treatment beam is generated using the pulse of optical radiation.

5. The method of claim 1 wherein a length of the resonator (L) is less than 2 meters.

6. The method of claim 1 further comprising using the pulse of optical radiation to pump a wavelength shifting resonator.

7. The method of claim 1 , wherein the one or more pigment particle target is a tattoo.

8. The method of claim 1 , wherein the one or more pigment particle target is a pigmented lesion.

9. The method of claim 1 , wherein the one or more pigment particle target is tissue changed by a skin disorder.

10. A method for treating pigment particles, the method comprising:

providing a picosecond pulse radiation source comprising a mode locked laser, wherein the mode locked laser is a multi transverse mode laser comprising,

a solid state crystal medium;

a resonator defined by two mirrors along a resonator optical axis, the solid state crystal medium disposed therein;

a fundamental frequency which is the speed of light divided by a round trip optical path length (2 L) of the resonator;

a mode locking element that is modulated at a frequency that is a sub-harmonic (l/n) of the fundamental frequency, which is the speed of light divided by round trip optical path length (2 L) where n is a whole number greater than 1;

generating a pulse of optical radiation, using the pulse radiation source, wherein the pulse has a duration of less than 1000 picoseconds; and

directing the pulse to one or more pigment particles to disrupt the target and promote clearance thereof.

11. The method of claim 10 , wherein the pulse is at least a 100 mJ/pulse.

12. The method of claim 10 wherein directing the pulse further comprises directing the pulse from the pulse radiation source through a treatment beam delivery system to one or more pigment particle target to disrupt the one or more pigment particle target and promote clearance thereof.

13. The method of claim 12 , wherein the treatment beam delivery system is operable to apply a treatment beam to tissue comprising a tattoo, a pigmented lesion, or a skin disorder, wherein the treatment beam is generated using the pulse of optical radiation.

14. The method of claim 10 , wherein a length of the resonator (L) is less than 2 meters.

15. The method of claim 10 , further comprising using the pulse of optical radiation to pump a wavelength shifting resonator.

16. The method of claim 10 , wherein the one or more pigment particle target is a tattoo.

17. The method of claim 10 , wherein the one or more pigment particle target is a pigmented lesion.

18. The method of claim 10 , wherein the one or more pigment particle target is tissue changed by a skin disorder.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2020
From: MIRKOV, MIRKO GEORGIEV; HOHM, DANIEL
To: CYNOSURE, INC.
Reel/Frame 053917/0444 →
CHANGE OF NAME Recorded Sep 29, 2020
From: CYNOSURE, INC.
To: CYNOSURE, LLC
Reel/Frame 053921/0565 →
Continuity (6)
Continuation 16363655 · Mar 25, 2019
Continuation 14340961 · Jul 25, 2014
Continuation 14216353 · Mar 17, 2014
Provisional Application 61891299 · Oct 15, 2013
Provisional Application 61789144 · Mar 15, 2013
Related Publication 20210038305A1 · Feb 11, 2021