IP Library Granted Patent US 11,724,013
Granted Patent B2
US 11,724,013 · App. 17/028,130 · Granted Aug 15, 2023

Fluid purification system

Inventors: Richard B. Peterson (Corvallis, OR); James R. Curtis (Portland, OR)
Assignee: Outset Medical, Inc.
A61M1/1686A61M1/1658A61M1/1672B01D61/08B01D61/18B01D61/58C02F1/001C02F1/02C02F1/20C02F1/283C02F1/441C02F1/444C02F9/20F24H1/121A61M2205/75B01D61/025B01D61/145B01D2311/04B01D2311/06B01D2311/25C02F2103/026C02F2209/005C02F2209/006C02F2209/03C02F2301/043C02F2301/046C02F2303/04
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Quick Facts
Patent No.
US 11,724,013
App. No.
17/028,130
Granted
Aug 15, 2023
Kind
B2
Abstract

Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.

Claims (16)

1. A fluid purification system comprising:

a pump adapted to pump household water through a pump outlet;

a microfluidic heat exchanger downstream of the pump and coupled to the fluid

flow pathway, the microfluidic heat exchanger comprising an inlet in fluid

communication with the pump outlet, an inflow microchannel downstream of the inlet, a heater downstream of the inflow microchannel, an outflow microchannel downstream of the heater and in thermal communication with the inflow microchannel to permit heat transfer between water flowing in the outflow microchannel and water flowing in the inflow microchannel, the microfluidic heat exchanger being configured to heat the water to a pasteurization temperature, maintain the water at the pasteurization temperature for a period of time effective to pasteurize the water, and cool the pasteurized water to a temperature lower than the pasteurization temperature; and

a mixer downstream of the microfluidic heat exchanger, the mixer comprising dialysate components for addition to water flowing from the microfluidic heat exchanger.

2. The system of claim 1 wherein the microfluidic heat exchanger further comprises a plurality of inflow microchannels in fluid communication with the inlet and a plurality of outflow microchannels in fluid communication with the mixer.

3. The system of claim 2 wherein the microchannels are disposed in a plurality of stacked laminae.

4. The system of claim 3 wherein the inflow microchannels and the outflow microchannels are separated by the laminae.

5. The system of claim 4 wherein the inflow microchannels and the outflow microchannels are formed from flow paths etched in facing surfaces of adjacent laminae.

6. The system of claim 3 wherein the microfluidic heat exchanger further comprises a heat transfer layer disposed between a lamina of inflow microchannels and a lamina of outflow microchannels.

7. The system of claim 3 wherein the inlet comprises an inlet opening extending through a plurality of laminae in fluid communication with the plurality of inflow microchannels in the plurality of laminae.

8. The system of claim 3 wherein the microfluidic heat exchanger further comprises an outlet opening extending through a plurality of laminae and in fluid communication with the plurality of outflow microchannels in the plurality of laminae and with the mixer.

9. The system of claim 3 wherein the microfluidic heat exchanger further comprises a heater region in which the heater is disposed, the heater region being in fluid communication with a plurality of laminae.

10. The system of claim 2 wherein the microfluidic heat exchanger further comprises a residence chamber comprising a flow pathway downstream of the heater and upstream of the outflow microchannels.

11. The system of claim 1 wherein the inlet microchannel and the outlet microchannel are disposed in a counterflow arrangement.

Assignments (10)
SECURITY INTEREST Recorded Jan 15, 2025
From: OUTSET MEDICAL, INC.
To: PERCEPTIVE CREDIT HOLDINGS IV, LP
Reel/Frame 069880/0739 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: GEMINO HEALTHCARE FINANCE, LLC
To: OUTSET MEDICAL, INC.
Reel/Frame 069800/0767 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2025
From: SLR INVESTMENT CORP., AS AGENT
To: OUTSET MEDICAL, INC.
Reel/Frame 069858/0267 →
SECURITY INTEREST Recorded Nov 4, 2022
From: OUTSET MEDICAL, INC.
To: GEMINO HEALTHCARE FINANCE, LLC
Reel/Frame 061654/0556 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 3, 2022
From: OUTSET MEDICAL, INC.
To: SLR INVESTMENT CORP., AS AGENT
Reel/Frame 061879/0764 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 15, 2021
From: OREGON STATE UNIVERSITY
To: OUTSET MEDICAL, INC.
Reel/Frame 058112/0875 →
CHANGE OF NAME Recorded Feb 12, 2021
From: HOME DIALYSIS PLUS, LTD.
To: OUTSET MEDICAL, INC.
Reel/Frame 055295/0140 →
CHANGE OF NAME Recorded Feb 12, 2021
From: STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY
To: OREGON STATE UNIVERSITY
Reel/Frame 055295/0138 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 12, 2021
From: CURTIS, JAMES R.
To: HOME DIALYSIS PLUS, LTD.
Reel/Frame 055244/0369 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 12, 2021
From: PETERSON, RICHARD B.; WANG, HAILEI; INGRAM-GOBLE, ROBBIE; FISHER, LUKE W.; GARRISON, ANNA E.
To: STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY
Reel/Frame 055244/0338 →
Continuity (6)
Division 16138441 · Sep 21, 2018
Division 14808827 · Jul 24, 2015
Continuation 13965720 · Aug 13, 2013
Continuation 13068038 · Apr 29, 2011
Continuation 12795382 · Jun 7, 2010
Related Publication 20210069401A1 · Mar 11, 2021
Cited By (1)
US 12,465,671