Adhesive film laminate
A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.
1. A surgical system, comprising:
a staple cartridge, comprising:
a cartridge body comprising a plurality of staple cavities; and
a plurality of staples positioned within said staple cavities;
an anvil configured for a facing relationship with said cartridge body, said anvil comprising at least one staple forming pocket;
an applicator;
a first tissue thickness compensator releasably attached to said cartridge body by an indefinitely flowable attachment portion, wherein said first tissue thickness compensator is positioned on a first side of said applicator prior to attachment to said cartridge body; and
a second tissue thickness compensator releasably attached to said anvil by a flowable adhesive, wherein said second tissue thickness compensator is positioned on a second side of said applicator opposite said first side prior to attachment to said anvil, wherein said applicator is configured to load said first tissue thickness compensator onto said staple cartridge and load said second tissue thickness compensator onto said anvil, and wherein said applicator comprises an alignment feature for aligning the first tissue thickness compensator with said staple cartridge and said second tissue thickness compensator with said anvil, and wherein one of said first tissue thickness compensator and said second tissue thickness compensator comprises a porous matrix, and wherein one of said first tissue thickness compensator and said second tissue thickness compensator comprises collagen.
2. The surgical system of claim 1 , wherein the flowable attachment portion is flowable at body temperature (37° C.) and/or room temperature (25° C.).
3. The surgical system of claim 1 , wherein the flowable attachment portion comprises a flowable polymeric composition that is solid up to 55° C.
4. The surgical system of claim 1 , wherein the flowable attachment portion comprises a flowable polymeric composition having an inherent viscosity from 0.6 to 4.0 dL/g in a 0.1 g/dL hexafluoroisopropanol solution at 25° C.
5. The surgical system of claim 1 , wherein the flowable attachment portion comprises a first profile and a second profile, wherein the second profile is complementary to a void in at least one of said cartridge body and said anvil.
6. The surgical system of claim 1 , wherein the flowable attachment portion comprises a first position and a second position, wherein the flowable attachment portion contacts an inner surface of said cartridge body when in the second position.
7. The surgical system of claim 1 , wherein the flowable attachment portion comprises an adhesive laminate comprising a base layer comprising the first tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the flowable attachment portion.
8. The surgical system of claim 1 , wherein the flowable attachment portion and the first tissue thickness compensator differ in at least one characteristic selected from composition, modulus, elongation, inherent viscosity, crystallinity, and bioabsorption.
9. The surgical system of claim 1 , wherein the flowable attachment portion comprises a pressure sensitive adhesive.
10. The surgical system of claim 9 , wherein the pressure sensitive adhesive comprises polylactide (PLA), polyglycolide (PGA), polycaprolactone (PCL), and combinations thereof.
11. The surgical system of claim 9 , wherein the pressure sensitive adhesive comprises a random copolymer comprising:
about 45 to about 55 mole percent ε-caprolactone, and balance glycolide.
12. The surgical system of claim 9 , wherein a concentration of glycolide in the pressure sensitive adhesive is at least 10 mole percent less than a concentration of glycolide in one of the first and second tissue thickness compensator.
13. The surgical system of claim 1 , wherein said staple cartridge further comprises a slot configured to slidably receive a cutting member therein, and wherein at least a portion of the flowable attachment portion is within the slot.
14. The surgical system of claim 1 , wherein at least a portion of the flowable adhesive is within the staple forming pocket.
15. The surgical system of claim 1 , wherein the flowable attachment portion releasably adheres the first tissue thickness compensator to the one of said cartridge body when the anvil is in a closed position.
16. The surgical system of claim 1 , wherein the first tissue thickness compensator releases from the one of said cartridge body when the flowable attachment portion is ruptured by a staple and/or a cutting member.
17. A surgical system, comprising:
a first jaw;
a second jaw, wherein one of said first jaw and said second jaw is movable relative to the other of said first jaw and said second jaw between an open position and a closed position;
a staple cartridge, comprising:
a cartridge body comprising a plurality of staple cavities; and
a plurality of staples positioned within said staple cavities;
an anvil configured for a facing relationship with said cartridge body, said anvil comprising at least one staple forming pocket;
an applicator;
a first buttress releasably attached to a first side of said applicator; and
a second buttress releasably attached to a second side of said applicator opposite said first side, wherein said applicator is configured to load said first buttress onto said first jaw such that said first buttress is releasably attached to said first jaw by a flowable adhesive, wherein said applicator is configured to load said second buttress onto said second jaw such that said second buttress is releasably attached to said second jaw by a flowable adhesive, wherein said applicator comprises an alignment feature for aligning the first buttress with said staple cartridge and said second buttress with said anvil, wherein one of said first buttress and said second buttress comprises a porous matrix, and wherein one of said first buttress and said second buttress comprises collagen.
18. The surgical system of claim 17 , wherein the flowable adhesive is flowable at body temperature (37° C.) and/or room temperature (25° C.).
19. The surgical system of claim 17 , wherein the flowable adhesive comprises a flowable polymeric composition that is solid up to 55° C.
20. The surgical system of claim 17 , wherein the flowable adhesive comprises a flowable polymeric composition having an inherent viscosity from 0.6 to 4.0 dL/g in a 0.1 g/dL hexafluoroisopropanol solution at 25° C.
21. The surgical system of claim 17 , wherein the flowable adhesive comprises a first profile and a second profile, wherein the second profile is complementary to a void in at least one of said cartridge body and said anvil.
22. The surgical system of claim 17 , wherein the flowable adhesive comprises a first position and a second position, wherein the flowable adhesive contacts an inner surface of said cartridge body when in the second position.
23. The surgical system of claim 17 , wherein the flowable adhesive and the first buttress differ in at least one characteristic selected from composition, modulus, elongation, inherent viscosity, crystallinity, and bioabsorption.
24. The surgical system of claim 17 , wherein the flowable adhesive comprises a random copolymer comprising:
about 45 to about 55 mole percent ε-caprolactone, and
balance glycolide.
25. The surgical system of claim 17 , wherein a concentration of glycolide in the flowable adhesive is at least 10 mole percent less than a concentration of glycolide in one of the first and second butresses.
26. The surgical system of claim 17 , wherein said staple cartridge further comprises a slot configured to slidably receive a cutting member therein, and wherein at least a portion of the flowable adhesive is within the slot.
27. The surgical system of claim 17 , wherein at least a portion of the flowable adhesive is within the staple forming pocket.
28. The surgical system of claim 17 , wherein the flowable adhesive releasably adheres the first buttress to said cartridge body when the anvil is in a closed position.
29. The surgical system of claim 17 , wherein the first buttress releases from said cartridge body when the flowable adhesive is ruptured by a staple and/or a cutting member.
30. A surgical system, comprising:
a first jaw;
a second jaw, wherein one of said first jaw and said second jaw is movable relative to the other of said first jaw and said second jaw between an open position and a closed position;
a staple cartridge, comprising:
a cartridge body comprising a plurality of staple cavities; and
a plurality of staples positioned within said staple cavities;
an anvil configured for a facing relationship with said cartridge body, said anvil comprising at least one staple forming pocket;
a first implantable adjunct; and
a second implantable adjunct, wherein said first implantable adjunct is releasably attached to said first jaw by a flowable adhesive, wherein said second implantable adjunct is releasably attached to said second jaw by a flowable adhesive, wherein one of said first implantable adjunct and said second implantable adjunct comprises a porous matrix, and wherein one of said first implantable adjunct and said second implantable adjunct comprises collagen.