IP Library Granted Patent US 11,414,622
Granted Patent B2
US 11,414,622 · App. 17/124,636 · Granted Aug 16, 2022

Free polyunsaturated fatty acid-containing composition and manufacturing method therefor

Inventors: Yuhei Kosuge (Tokyo, JP); Hideaki Yamaguchi (Tokyo, JP); Nobushige Doisaki (Tokyo, JP)
Assignee: NIPPON SUISAN KAISHA, LTD.
C11C3/00A23D9/007A23L33/12A61K31/201A61K31/202C07C57/12C07C69/58A23V2002/00
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Quick Facts
Patent No.
US 11,414,622
App. No.
17/124,636
Granted
Aug 16, 2022
Kind
B2
Abstract

The present disclosure is: a free polyunsaturated fatty acid-containing composition, which comprises at least one free polyunsaturated fatty acid having 20 or more carbon atoms, the content being at least 80.0% of the fatty acids in the composition, and satisfies at least one selected from a group consisting of conditions (1) and (2): (1) the content of conjugated unsaturated fatty acid is 1.0% or less of the fatty acids in the composition, and (2) the Gardner color is less than 3+; and a manufacturing method for the free polyunsaturated fatty acid-containing composition comprising the preparation of a raw material composition containing at least one polyunsaturated fatty acid having 20 or more carbon atoms, and hydrolysis of a reaction solution containing the prepared raw material composition, a lower alcohol, water and an alkali catalyst at a temperature of 10° C. or lower.

Claims (8)

1. A free polyunsaturated fatty acid-containing composition, comprising free eicosapentaenoic acid in an amount that a content thereof is 80.0% or greater of fatty acids in the composition, wherein the composition satisfies at least one selected from the group consisting of conditions (1) and (2):

(1) a content of a conjugated unsaturated fatty acid being 0.001% to 1.0% of the fatty acids in the composition; and

(2) a Gardner color being less than 6−.

2. The free polyunsaturated fatty acid-containing composition according to claim 1 , wherein the composition has an anisidine value of 5.0 or less.

3. The free polyunsaturated fatty acid-containing composition according to claim 1 , wherein a content of a fatty acid alkyl ester is 0.2% or less of the fatty acids in the composition.

4. The free polyunsaturated fatty acid-containing composition according to claim 1 , wherein the content of the conjugated unsaturated fatty acid is from 0.01% to 0.8% of the fatty acids in the composition.

5. The free polyunsaturated fatty acid-containing composition according to claim 1 , wherein a total content of a residual organic solvent in the composition is 5000 ppm or less.

6. The free polyunsaturated fatty acid-containing composition according to claim 1 , wherein a content of a di- or higher-valent polyunsaturated fatty acid having 18 carbons in the composition is 2.0% or less of the fatty acids in the composition.

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNEE'S COUNTRY FROM UNITED STATES TO JAPAN PREVIOUSLY RECORDED ON REEL 054680 FRAME 0381. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 29, 2021
From: KOSUGE, YUHEI; YAMAGUCHI, HIDEAKI; DOISAKI, NOBUSHIGE
To: NIPPON SUISAN KAISHA, LTD.
Reel/Frame 055760/0115 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2020
From: KOSUGE, YUHEI; YAMAGUCHI, HIDEAKI; DOISAKI, NOBUSHIGE
To: NIPPON SUISAN KAISHA, LTD.
Reel/Frame 054680/0381 →
Priority Claims (1)
JP JP2015-170856 · Aug 31, 2015 · national
Continuity (4)
Continuation 16752048 · Jan 24, 2020
Continuation 15906602 · Feb 27, 2018
Continuation PCTJP2016075444 · Aug 31, 2016
Related Publication 20210102142A1 · Apr 8, 2021