IP Library Granted Patent US 11,554,133
Granted Patent B2
US 11,554,133 · App. 17/171,545 · Granted Jan 17, 2023

Bile acid synthesis promoter, composition for promoting bile acid synthesis and food composition for promoting bile acid synthesis

Inventors: Shimpei Watanabe (Tokyo, JP); Satoshi Inamasu (Tokyo, JP); Mitsuhiro Watanabe (Kanagawa, JP); Yoko Takashina (Kanagawa, JP)
Assignee: KRACIE HOLDINGS, LTD.
A61K31/7048A61K31/365A61P1/16
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Quick Facts
Patent No.
US 11,554,133
App. No.
17/171,545
Granted
Jan 17, 2023
Kind
B2
Abstract

[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversion of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).

Claims (5)

1. A method for promoting bile acid excretion comprising:

administering a pharmaceutically effective amount arctigenin and/or arctiin to a subject in need of such treatment, wherein the subject in need of such treatment is a person diagnosed with angina or cerebral hemorrhage.

2. The method according to claim 1 , comprising said arctigenin and/or arctiin as burdock, burdock fruit, burdock sprout or Forsythia fruit or extracts thereof.

3. The method according to claim 1 , comprising administering parenterally.

4. The method according to claim 1 , comprising administering orally.

Assignments (2)
CHANGE OF NAME Recorded Jun 13, 2024
From: KRACIE HOLDINGS, LTD.
To: KRACIE, LTD.
Reel/Frame 067714/0179 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2021
From: WATANABE, SHIMPEI; INAMASU, SATOSHI; WATANABE, MITSUHIRO; TAKASHINA, YOKO
To: KRACIE HOLDINGS, LTD.
Reel/Frame 055201/0597 →
Priority Claims (1)
JP JP2017-050744 · Mar 16, 2017 · national
Continuity (2)
Division 16493906
Related Publication 20210161931A1 · Jun 3, 2021