IP Library Granted Patent US 11,839,745
Granted Patent B2
US 11,839,745 · App. 17/373,998 · Granted Dec 12, 2023

System and method for body mass index relation to patient differing psychological stress effect on blood glucose dynamics in patients with insulin dependent diabetes

Inventors: Stephen D. Patek (Charlottesville, VA); Basak Ozaslan (Charlottesville, VA); Linda Gonder-Frederick (Charlottesville, VA)
Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
A61M5/1723A61M5/14276G16H20/17G16H50/30G16H50/70A61M2205/3553A61M2205/3569A61M2205/3584A61M2230/201
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Quick Facts
Patent No.
US 11,839,745
App. No.
17/373,998
Granted
Dec 12, 2023
Kind
B2
Abstract

An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data.

Claims (48)

1. An insulin dispensing device, comprising:

a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

a sensor configured to generate a blood glucose level measurement, wherein the sensor is calibrated as a function of the psychological stress level data and the BMI data, and wherein the processor is configured to:

monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and

identify a BMI value that counteracts a detected change in the blood glucose level measurement; and

wherein the processor is configured to change the insulin dosing schedule information in accordance with the counteracting BMI data.

2. The insulin dispensing device of claim 1 , wherein the insulin dosing schedule information is input.

3. The insulin dispensing device of claim 1 in combination with:

an insulin pump, wherein the insulin dosing schedule information is received from the insulin pump.

4. The insulin dispensing device of claim 1 , wherein the psychological stress level data is measured on a scale.

5. The insulin dispensing device of claim 4 , wherein the scale is a five point Likert scale.

6. The insulin dispensing device of claim 1 , wherein the processor is configured to correlate a detected increase in a value of the psychological stress level data with an increase in a value of the blood glucose level measurement.

7. The insulin dispensing device of claim 1 , wherein the processor is configured to correlate a detected decrease in a value of the psychological stress level data with a decrease in a value of the blood glucose level measurement.

8. The insulin dispensing device of claim 1 , wherein the processor is configured to correlate a counteraction of a BMI data increase with an increase in a value of the BMI data.

9. The insulin dispensing device of claim 8 , wherein the processor is configured to detect a decrease in a value of a blood glucose level measurement data when the increase in the value of the BMI data crosses a threshold.

10. The insulin dispensing device of claim 1 , wherein the processor is configured to correlate the counteraction by a BMI data with a higher uptake of glucose.

11. The insulin dispensing device of claim 1 in combination with:

a display, wherein the processor is configured to categorize and display the BMI data as normal BMI, overweight BMI, or obese BMI.

12. A method for controlling insulin dispensing based on insulin sensitivity, the method comprising:

receiving insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

generating a blood glucose level measurement as a function of the psychological stress level data and the BMI data;

monitoring and detecting changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data;

identifying a BMI value that counteracts a detected change in the blood glucose level measurement;

updating the insulin dosing schedule information in accordance with the counteracting BMI data; and

controlling insulin dispensing to provide insulin dosing based on the updated insulin dosing schedule information.

13. The method of claim 12 wherein:

a processor receives the insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data.

14. The method of claim 12 wherein:

a sensor generates the blood glucose level measurement.

15. The method of claim 12 wherein:

a processor monitors and detects changes of the blood glucose level measurement.

16. The method of claim 12 wherein:

a processor identifying the BMI value that counteracts the detected change in the blood glucose level measurement.

17. The method of claim 12 wherein:

an insulin dispensing device performs the insulin dispensing.

18. A non-transitory computer readable recording medium encoded with a computer program including instructions causing control of insulin dispensing for an insulin dispensing device based on insulin sensitivity, the program causing the insulin dispensing device to:

receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

generate a blood glucose level measurement as a function of the psychological stress level data and the BMI data;

monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data;

identify a BMI value that counteracts a detected change in the blood glucose level measurement;

update the insulin dosing schedule information in accordance with the counteracting BMI data; and

control insulin dispensing to provide insulin dosing based on the updated insulin dosing schedule information.

19. A non-transitory computer readable recording medium encoded with a computer program including instructions causing control of glucose monitoring for a glucose monitoring device, the program causing the glucose monitoring device to:

receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data;

generate a blood glucose level measurement as a function of the psychological stress level data and the BMI data; and

monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data.

20. The non-transitory computer readable recording medium of claim 19 , wherein the program causes the glucose monitoring device to:

identify a BMI value that counteracts a detected change in the blood glucose level measurement.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2021
From: PATEK, STEPHEN D.; OZASLAN, BASAK; GONDER-FREDERICK, LINDA
To: UNIVERSITY OF VIRGINIA
Reel/Frame 056836/0102 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 13, 2021
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 056836/0179 →
Continuity (3)
Continuation 16485989
Provisional Application 62459096 · Feb 15, 2017
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