IP Library › Granted Patent US 11,918,830
Granted Patent B2
US 11,918,830 · App. 17/382,044 · Granted Mar 5, 2024

Proton therapy tuning apparatus and method of use thereof

Inventors: Susan L. Michaud (Brewster, MA); Daniel J. Raymond (Windham, NH); Artur Teymurazyan (Shrewsbury, MA); Ran Tu (Malden, MA)
A61N5/1077A61B6/03A61N5/1044A61N5/1067A61N5/1082G21K1/087G21K1/093G21K5/04A61N5/107A61N2005/1074A61N2005/1087A61N2005/1097H01J35/147
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Quick Facts
Patent No.
US 11,918,830
App. No.
17/382,044
Granted
Mar 5, 2024
Kind
B2
Abstract

The invention comprises a method and apparatus for tuning a charged particle beam path of a charged particle beam system used to treat a tumor of a patient, comprising the steps of: positioning a two-dimensional charged particle detector in a beam line downstream from a magnet pair; operating windings of the magnet pair at a first power level to generate a first magnetic field; measuring a beam position with the first two-dimensional charged particle detector; adjusting a correction magnetic field by driving voltage of a correction coil at a second power level, the second power level less than five percent of the first power level, where the first magnetic field and the correction magnetic field combine to yield an operational magnetic field; and the steps of measuring and adjusting the correction magnetic field changing the operational magnetic field to adjust a measured beam position toward a target beam position.

Claims (30)

1. A method for tuning a positively charged particle beam path in a gap of a charged particle beam system used to treat a tumor of a patient with positively charged particles, comprising the steps of:

positioning a first two-dimensional charged particle detector in a beam line downstream from a first upstream magnet pair of a cancer therapy system, said beam line running at least from an injector, through a synchrotron, and along a beam transport line to a patient position;

operating windings of said first upstream magnet pair at a first power level to generate a first magnetic field across the gap;

measuring a beam position with said first two-dimensional charged particle detector;

adjusting a correction magnetic field by driving voltage of a correction coil at a second power level, said second power level less than five percent of said first power level, wherein the first magnetic field and the correction magnetic field combine to yield an operational magnetic field during use; and

said steps of measuring and adjusting the correction magnetic field changing the operational magnetic field to adjust a measured beam position toward a target beam position.

2. The method of claim 1 , further comprising the steps of:

altering a voltage of a second upstream magnet pair to yield an altered magnetic field about the positively charged particle beam path; and

said steps of measuring, adjusting, and altering moving the positively charged particle beam path toward a target beam position.

3. The method of claim 1 , further comprising the steps of:

passing a current through an organic semi-conducting film of said first two-dimensional charged particle detector.

4. The method of claim 1 , further comprising the step of:

said step of positioning, placing at least a mounting element of said first two-dimensional charged particle detector between a flattened coil end of said first upstream magnet pair and a downstream magnet pair, said first upstream magnet pair comprising a core and a first winding, said first winding comprising a first width and a first thickness along a path parallel to the gap and a second width and a second thickness in a space between said first upstream magnet pair and said downstream magnet pair, said first width greater than 1.5 times said second width and said second thickness greater than 1.5 times said first thickness.

5. The method of claim 1 , further comprising the steps of:

placing a set of two-dimensional charged particle detectors, comprising said first two-dimensional charged particle detector, in said beam line;

tuning said beam line of said cancer therapy system with said set of two-dimensional charged particle detectors; and

without removing said set of two-dimensional charged particle detectors from said beam line, dynamically tuning said beam line during a treatment session of the patient.

6. The method of claim 1 , further comprising the step of:

auto-tuning the positively charged particle beam path, said step of auto-tuning comprising the steps of:

measuring an incorrect beam shape of the charged particle beam path with said first two-dimensional charged particle detector;

selecting a condition-action rule, based upon a classification of said incorrect beam shape; and

applying a first altered voltage, according to the selected condition-action rule, to said first upstream magnet pair to adjust the operational magnetic field to yield an at least partially corrected beam shape of the charged particle beam path.

7. The method of claim 6 , further comprising the step of:

altering a supplied voltage, according to the selected condition-action rule, to a first downstream magnet pair to further adjust the operational magnetic field to further correct the charged particle beam path.

8. The method of claim 5 , comprising the step of:

determining an altered beam alignment from a planned beam alignment during a treatment session of the tumor of the patient;

recording at least one missed tumor voxel, resultant from the determined altered beam alignment, during the treatment session; and

dynamically altering magnet fields of the cancer therapy system to treat said missed tumor voxel.

9. The method of claim 1 , further comprising the step of:

treating the tumor with the positively charged particles, where greater than ninety-percent of the positively charged particles in the treatment pass entirely through the patient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2023
From: MICHAUD, SUSAN L; RAYMOND, DANIEL J; TEYMURAZYAN, ARTUR; TU, RAN
To: PROTOM INTERNATIONAL HOLDING CORPORATION
Reel/Frame 062379/0007 →
Continuity (16)
Continuation In Part 16903736 · Jun 17, 2020
Continuation In Part 16533761 · Aug 6, 2019
Continuation In Part 15901788 · Feb 21, 2018
Continuation In Part 15892240 · Feb 8, 2018
Continuation In Part 15868897 · Jan 11, 2018
Continuation In Part 15838072 · Dec 11, 2017
Continuation In Part 15823148 · Nov 27, 2017
Continuation In Part 15467840 · Mar 23, 2017
Continuation In Part 15402739 · Jan 10, 2017
Continuation In Part 15348625 · Nov 10, 2016
Continuation In Part 15167617 · May 27, 2016
Continuation 15152479 · May 11, 2016
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13087096 · Apr 14, 2011
Provisional Application 61324776 · Apr 16, 2010
Related Publication 20210353966A1 · Nov 18, 2021
Cited By (2)
US 12,447,358 US 12,569,700