IP Library › Granted Patent US 12,433,988
Granted Patent B2
US 12,433,988 · App. 17/392,804 · Granted Oct 7, 2025

Methods and systems for high-throughput blood component collection

Inventors: Thomas J. Felt (Boulder, CO); Dennis J. Hlavinka (Arvada, CO); Brian M. Holmes (Evergreen, CO)
Assignee: Terumo BCT, Inc.
A61M1/3696A61M1/024A61M1/0272A61M1/304A61M1/3496A61M1/3601A61M1/36224A61M1/362261A61M1/362262A61M1/362265A61M1/3627A61M1/3646A61M1/3693A61M1/382A61M1/30A61M1/3403A61M1/36222A61M1/3639A61M2202/0415A61M2205/12A61M2205/123A61M2205/331A61M2205/3334A61M2205/3379A61M2205/50
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Quick Facts
Patent No.
US 12,433,988
App. No.
17/392,804
Granted
Oct 7, 2025
Kind
B2
Abstract

Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

Claims (12)

1. A blood component collection set associated with an apheresis system comprising:

a needle configured to draw whole blood from a-doner whole blood source;

a first tube having a lumen fluidly associated with the needle, the first tube being configured to move the whole blood through the lumen after a draw pump engaged with the first tube draws the whole blood from the whole blood source;

a blood component collection bladder configured to be inserted into a centrifuge and fluidly associated with the first tube, the blood component collection bladder being configured to separate the whole blood into a first blood component including plasma and a second blood component;

a second tube fluidly associated with the blood component collection bladder, the second tube being configured to move the first blood component from the blood component collection bladder; and

a collection container fluidly associated with the second tube that extracts the first blood component from the apheresis system, wherein

the second tube is further configured to move the first blood component back towards the blood component collection bladder through the second tube to move at least the second blood component from the blood component collection bladder back into the whole blood source.

2. The blood component collection set of claim 1 , wherein the second blood component is platelets.

3. The blood component collection set of claim 1 , wherein the draw pump is disengaged when a return pump forces the first blood component back towards the blood component collection bladder through the second tube to move at least the second blood component from the blood component collection bladder and back into the whole blood source.

4. The blood component collection set of claim 1 , wherein the blood component collection bladder is inserted and held in a filler, in the centrifuge, that spins the blood component collection bladder.

5. The blood component collection set of claim 1 , wherein the apheresis system includes a sensor is positioned in physical proximity to the second tube to detect when a third blood component is being extracted from the whole blood.

6. The blood component collection set of claim 5 , wherein the second tube is configured to move the first blood component back towards the blood component collection bladder after the second blood component is detected by the sensor and while the centrifuge continues to spin.

Continuity (4)
Division 15958851 · Apr 20, 2018
Provisional Application 62539053 · Jul 31, 2017
Provisional Application 62488404 · Apr 21, 2017
Related Publication 20210361847A1 · Nov 25, 2021
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