Ring-opening polymerizations using a flow reactor
Techniques regarding the synthesis of one or more polymers through one or more ring-opening polymerizations conducted within a flow reactor and facilitated by one or more anionic catalysts are provided. For example, one or more embodiments can comprise a method, which can comprise polymerizing, via a ring-opening polymerization within a flow reactor, a cyclic monomer in the presence of one or more anionic organocatalysts.
1. A method, comprising:
polymerizing, via a ring-opening polymerization within a flow reactor, a cyclic monomer in the presence of an anionic organocatalyst characterized by a chemical structure:
wherein X corresponds to an anion selected from a first group consisting of an oxygen anion, a sulfur anion, and a nitrogen anion;
wherein L corresponds to an atom selected from a second group consisting of a carbon atom and a nitrogen atom;
wherein R 1 corresponds to a first functional group selected from a third group consisting of a first alkyl group and a first aryl group;
wherein R 2 corresponds to a second functional group selected from a fourth group consisting of a second alkyl group and a second aryl group; and
wherein R 3 corresponds to a third functional group selected from a fifth group consisting of a third alkyl group and a third aryl group.
2. The method of claim 1 , wherein the cyclic monomer is selected from a sixth group consisting of a lactone monomer, a cyclic carbonate monomer, a substituted cyclic carbonate monomer, a cyclic phospholane monomer, a morpholinone monomer, tetrahydro-2H-pyran-2-thione, oxepane-2-thione, tetrahydrothiopyranone, and 2-thiepanone.
3. The method of claim 1 , wherein the anionic organocatalyst is derived from a chemical reaction between a chemical compound and a chemical base, wherein the chemical base is selected from a sixth group consisting of 1,8-diazabicyclo[5.4.0]undec-7-ene, 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene, phosphazene bases, 1,3,2-diazaphosphorin-2-amin, 2-[(1,1-dimethylethyl)imino]-N,N-diethyl-1,2,2,2,3,4,5,6-octahydro-1,3-dimethyl, 1,3-dihydro-1,3-bis(2,4,6-trimethylphenyl)imidazole-2-ylidene, potassium methoxide, potassium hydride, sodium methoxide, and sodium hydride.
4. The method of claim 1 , further comprising:
reacting, via a second ring-opening polymerization within the flow reactor, an intermediate polymer with a second cyclic monomer in the presence of a chemical compound to form a block copolymer, and wherein the intermediate polymer is formed from the polymerizing the cyclic monomer.
5. The method of claim 4 , wherein the reacting comprises protonating the anion via a proton transfer with the chemical compound to form a second anionic organocatalyst, and wherein the second anionic organocatalyst is a catalyst to the second ring-opening polymerization.