IP Library › Granted Patent US 12,037,685
Granted Patent B2
US 12,037,685 · App. 17/411,545 · Granted Jul 16, 2024

Liquid chromatography system and component

Inventor: Gary A. Barone (State College, PA)
Assignee: Silcotek Corp
C23C16/45523C23C16/24C23C16/045
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Quick Facts
Patent No.
US 12,037,685
App. No.
17/411,545
Granted
Jul 16, 2024
Kind
B2
Abstract

Liquid chromatography systems and liquid chromatography components are disclosed. In an embodiment, a liquid chromatography system includes a liquid chromatography component. The liquid chromatography component includes a substrate and an amorphous coating on the substrate. The amorphous coating has a base layer and a surface layer. The base layer includes carboxysilane.

Claims (34)

1. A liquid chromatography system, comprising:

a liquid chromatography component, comprising:

a substrate; and an amorphous coating on the substrate,

wherein the amorphous coating is positioned on regions of the liquid chromatography component that are unable to be concurrently coated through line-of-sight techniques;

wherein the amorphous coating comprises carbon, hydrogen, silicon, and oxygen and includes less than 6 particles having a dimension of greater than 0.5 micrometers within a 100 square micrometer region.

2. The liquid chromatography system of claim 1 , wherein the substrate is metal or metallic.

3. The liquid chromatography system of claim 1 , wherein the substrate is stainless steel.

4. The liquid chromatography system of claim 1 , wherein the substrate is an aluminum alloy.

5. The liquid chromatography system of claim 1 , wherein the substrate includes titanium.

6. The liquid chromatography system of claim 1 , wherein the substrate includes, by weight, at least 15% cobalt.

7. The liquid chromatography system of claim 1 , wherein liquid chromatography component is tubing.

8. The liquid chromatography system of claim 1 , wherein liquid chromatography component has channels.

9. The liquid chromatography system of claim 1 , wherein liquid chromatography component has curves.

10. The liquid chromatography system of claim 1 , wherein liquid chromatography component has threading.

11. The liquid chromatography system of claim 1 , wherein liquid chromatography component has protrusions.

12. The liquid chromatography system of claim 1 , wherein liquid chromatography component has cavities.

13. The liquid chromatography system of claim 1 , wherein liquid chromatography component has junctions.

14. The liquid chromatography system of claim 1 , wherein liquid chromatography component has mating surfaces.

15. The liquid chromatography component of claim 1 .

16. The liquid chromatography system of claim 1 , wherein the substrate is metal or metallic.

17. The liquid chromatography system of claim 1 , wherein the substrate is stainless steel.

18. The liquid chromatography component of claim 1 .

19. A liquid chromatography system, comprising:

a liquid chromatography component having a non-line-of-sight geometry, the liquid chromatography component comprising:

a substrate; and

an amorphous coating on the substrate throughout the non-line-of-sight geometry,

wherein the amorphous coating comprises carbon, hydrogen, silicon, and oxygen and includes less than 6 particles having a dimension of greater than 0.5 micrometers within a 100 square micrometer region;

wherein the substrate is stainless steel.

20. A liquid chromatography system, comprising:

a liquid chromatography component having a non-line-of-sight geometry, the liquid chromatography component comprising:

a stainless steel substrate; and

an amorphous coating on the stainless steel substrate throughout the non-line-of-sight geometry,

wherein the amorphous coating comprises carbon, hydrogen, silicon, and oxygen and includes less than 6 particles having a dimension of greater than 0.5 micrometers within a 100 square micrometer region;

wherein the substrate is stainless steel.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 14, 2024
From: BARONE, GARY A.
To: SILCOTEK CORP
Reel/Frame 067408/0884 →
Continuity (4)
Continuation 16870034 · May 8, 2020
Continuation 15755962
Provisional Application 62212868 · Sep 1, 2015
Related Publication 20210381105A1 · Dec 9, 2021
Cited By (1)
US 12,291,778