IP Library › Granted Patent US 12,217,427
Granted Patent B2
US 12,217,427 · App. 17/423,157 · Granted Feb 4, 2025

Method of visualizing a dynamic anatomical structure

Inventors: Marcus Schreckenberg (Freising, DE); Niklas Hitschrich (Eindhoven, NL)
Assignee: KONINKLIJKE PHILIPS N.V.
G06T7/0016G06T7/11G06T15/08G06T19/006G06V10/25G06V10/62G06T2207/10016G06T2207/10076G06T2207/30048G06V2201/031
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Quick Facts
Patent No.
US 12,217,427
App. No.
17/423,157
Granted
Feb 4, 2025
Kind
B2
Abstract

The invention relates to a method of visualising a dynamic anatomical structure ( 1 ), a computer program and a user interface. The method comprises (a) providing a sequence of three-dimensional medical images (M 1 , M 2 , M 3 , . . . MZ) of a dynamic anatomical structure ( 1 ) spanning a time period (T), (b) providing a dynamic model ( 14 ), in particular surface of the anatomical structure, (c) determining a volume of interest ( 40 ) containing an anatomical feature of interest ( 3 ) within each of the three-dimensional images, wherein the volume of interest ( 40 ) follows the position and/or the shape of the anatomical feature of interest ( 3 ) across the time period and wherein the volume of interest ( 40 ) is smaller than the complete field of view of the three-dimensional medical images (M 1 , M 2 , M 3 , . . . MZ), and (d) providing a three-dimensional visualisation environment ( 50, 70 ), wherein a visualisation ( 45 ) corresponding to a particular point in time comprises (i) a volume rendering of the volume of interest ( 40 ) of the three-dimensional image; and (ii) a visualisation of the dynamic model ( 14 ) in the same coordinate system. Preferably, the three-dimensional visualisation environment ( 50, 70 ) allows for displaying the dynamic model ( 14 ) and the volume rendered volume of interest ( 40 ) for each three-dimensional image across the time period in cine mode.

Claims (39)

1. A method of visualising a dynamic anatomical structure, the method comprising:

a) providing a sequence of three-dimensional medical images spanning a time period, each three-dimensional medical image of the sequence showing a dynamic anatomical structure at a point in time during the time period;

b) providing a dynamic model of at least a part of the dynamic anatomical structure, wherein the dynamic model has been derived from and is registered with the sequence of three-dimensional medical images;

c) determining a volume of interest containing an anatomical feature of interest within each of the three-dimensional medical images, wherein the volume of interest follows a position and/or a shape of the anatomical feature of interest across the time period, and wherein the volume of interest is smaller than a complete field of view of the three-dimensional medical images; and

d) providing a three-dimensional visualisation environment for displaying the dynamic anatomical structure across the time period, wherein a visualisation corresponding to a particular point in time within the time period comprises

(i) a volume rendering of the volume of interest of the three-dimensional medical image corresponding to the particular point in time; and

(ii) a visualisation of the dynamic model at the particular point in time and in the same coordinate system as the volume rendering of the volume of interest.

2. The method of claim 1 , wherein the three-dimensional visualisation environment is a virtual reality environment.

3. The method of claim 2 , wherein the virtual reality environment comprises at least one input tool, wherein the input tool is realised by a virtual reality controller and allows a user to grab and move an object within the virtual reality environment using hand gestures.

4. The method of claim 2 , wherein the virtual reality environment comprises at least one input tool, wherein the input tool is realised by a virtual reality controller and allows a user to adjust parameters used in the visualisation of the dynamic model via gesture control.

5. The method of claim 4 , wherein the gesture control is to adjust settings for a threshold used in performing volume rendering on the volume of interest.

6. The method of claim 1 , wherein the dynamic anatomical structure is a human heart or animal heart, and the anatomical feature of interest is a part of the human heart or animal heart.

7. The method of claim 6 , wherein the dynamic model is a dynamic surface model of one heart chamber or several heart chambers, and the anatomical feature is a heart valve.

8. The method of claim 1 , wherein the dynamic model is a dynamic surface model and is derived from the sequence of three-dimensional medical images by segmentation over all three-dimensional medical images, or by segmentation in one three-dimensional medical image and speckle or feature tracking in subsequent three-dimensional medical images.

9. The method of claim 1 , wherein a position and/or orientation of the volume of interest is determined across the time period by identifying a corresponding position and/or orientation of the anatomical feature of interest in the dynamic model.

10. The method of claim 1 , wherein the volume of interest is determined by identifying a set of landmark points of the anatomical feature in the dynamic model or in the three-dimensional medical images, wherein the landmark points follow the position and/or the shape of the anatomical feature of interest across the time period, and by defining a approximating surface spanning the set of landmark points for each three-dimensional medical image, and by determining the volume of interest as a volume extending above and/or below and/or to a side of the approximation surface.

11. The method of claim 1 , wherein providing a three-dimensional visualisation environment comprises:

displaying a computer graphical object corresponding to a medical device in the same coordinate system as the volume rendering of the volume of interest, and wherein the computer graphical object is locked to a position in the dynamic model when the dynamic model and the volume rendered volume of interest are displayed in cine-mode, and

providing an input tool to a user, the input tool allowing the user to move and tilt the computer graphical object corresponding to the medical device in relation to the volume rendering and the visualisation of the dynamic model.

12. The method of claim 11 , wherein the medical device comprises an implant.

13. The method of claim 1 , wherein providing a three-dimensional visualisation environment comprises:

providing an input tool to a user, the input tool allowing the user to select points within the dynamic anatomical structure and to take measurements on the dynamic anatomical structure.

14. A tangible, non-transitory computer readable medium that stores a computer program comprising program code instructions which, when executed by a processor, enables the processor to perform the method according to claim 1 .

15. A user interface configured for visualising a dynamic anatomical structure, the dynamic anatomical structure having been captured on a sequence of three-dimensional medical images spanning a time period, each three-dimensional medical image of the sequence showing the dynamic anatomical structure at a point in time during the time period,

the user interface comprising:

a) a three-dimensional visualisation environment configured to provide a three-dimensional visualisation of the dynamic anatomical structure across a time period, and

a processor configured for generating a visualisation corresponding to a particular point in time within the time period, the visualisation comprising:

(i) a display of a volume rendering of a volume of interest within the three-dimensional medical image corresponding to the particular point in time, the volume of interest containing an anatomical feature of interest; and

(ii) a display of a dynamic model of at least a part of the dynamic anatomical structure at the particular point in time and in the same coordinate system as the volume rendering of the volume of interest,

wherein the volume of interest follows a position and/or a shape of the anatomical feature of interest across the time period, and wherein the volume of interest is smaller than a complete field of view of the three-dimensional medical images.

16. The user interface of claim 15 , wherein the three-dimensional visualisation environment is a virtual reality environment and the display of the volume rendering of the volume of interest and the dynamic model is a virtual reality display.

17. The user interface of claim 16 , wherein the virtual reality environment comprises at least one input tool, wherein the input tool is a virtual reality controller allowing a user to perform one or more of the following actions:

to grab and move an object displayed in the virtual reality environment;

to take measurements on the dynamic anatomical structure;

to adjust parameters used in the visualisation of the dynamic model via gesture control; and

to make annotations to the dynamic anatomical structure, wherein the annotations are locked to a position in the dynamic model when the dynamic model and the volume rendered volume of interest are displayed in cine-mode.

18. The user interface of claim 16 , wherein the virtual reality display is provided on a virtual reality headset.

19. The user interface of claim 15 , wherein the dynamic model is a dynamic surface model of one heart chamber or several heart chambers, and the anatomical feature is a heart valve.

20. The user interface of claim 15 , wherein the dynamic model is a dynamic surface model and is derived from the sequence of three-dimensional medical images by segmentation over all three-dimensional medical images, or by segmentation in one three-dimensional medical image and speckle or feature tracking in subsequent three-dimensional medical images.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2021
From: SCHRECKENBERG, MARCUS; HITSCHRICH, NIKLAS
To: KONINKLIJKE PHILIPS N.V.
Reel/Frame 056863/0389 →
Priority Claims (1)
EP 19152222 · Jan 17, 2019 · regional
Continuity (1)
Related Publication 20220130046A1 · Apr 28, 2022
References Cited (33)
US 8103070B2 · Roberts · 2012 [cited by applicant]
US 11207133B1 · Douglas · 2021 [cited by examiner]
US 11801114B2 · Lang · 2023 [cited by examiner]
US 20050253841A1 · Brabec · 2005 [cited by applicant]
US 20080194957A1 · Hoctor · 2008 [cited by applicant]
US 20110103661A1 · Schummers · 2011 [cited by applicant]
US 20110107270A1 · Wang · 2011 [cited by examiner]
US 20110201915A1 · Gogin et al. · 2011 [cited by applicant]
US 20140052001A1 · Ionasec · 2014 [cited by applicant]
US 20150140535A1 · Geri et al. · 2015 [cited by applicant]
US 20160125640A1 · Lee et al. · 2016 [cited by applicant]
US 20160220311A1 · Mansi · 2016 [cited by applicant]
US 20170084023A1 · Wachter-Stehle · 2017 [cited by applicant]
CN 103236058A · 2013 [cited by examiner]
CN 103429164A · 2013 [cited by examiner]
CN 106600596 · 2019 [cited by examiner]
JP 2001128982A1 · 2001 [cited by applicant]
JP 2012217780A · 2012 [cited by applicant]
International Search Report and Written Opinion of PCT/PCT/EP2020/050604, dated Mar. 20, 2020. [cited by applicant]
Sorensen, Thomas Sangild et al “A New Virtual Reality Approach for Planning of cardiac Interventions”, Artificial Intelligence in Medicine, vol. 22, 2001, pp. 193-214. [cited by applicant]
Lin, Wei-te et al “Visualization of Cardiac Dynamics using Physics-based Deformable Model”, Medical Imaging Image Display and Visualization, vol. 3976, 2000. [cited by applicant]
Linte, Cristian A. et al “Virtual Reality-Enhanced Ultrasound Guidance: A Novel Technique for Intracardiac Interventions” Computer Aided Surgern, vol. 13, No. 2, Mar. 2008, pp. 82-94. [cited by applicant]
Peters, Terry M. et al “Towards a Medical Virtual Reality Environment for Minimally Invasive Cardiac Surgery”, MIAR 2008, Incs 5128, pp. 1-11. [cited by applicant]
Abiri, Arash et al “Simulating Developmental Cardiac Morphology in Virtual Reality Using a Deformable Image Registration Approach”, Annals of Biomedical Engineering, 2018. [cited by applicant]
Noorani, Alia et al “Challenges in valve-in-valve therapy,” J. Thorac. Dis., vol. 7, No. 9, pp. 1501-1508, 2015. [cited by applicant]
Dvir, Danny et al “Transcatheter Aortic Valve-in-Valve Implantation for Patients With Degenerative Surgical Bioprosthetic Valves,” Curr. Probl. Cardiol., vol. 39, No. 1, pp. 7-27, 2014. [cited by applicant]
Mahmood, Feroze. et at, “Three-dimensional printing of mitral valve using echocardiographic data,” JACC Cardiovasc. Imaging, vol. 8, No. 2, pp. 227-229, 2015. [cited by applicant]
D. Dvir and J. Webb, “Mitral valve-in-valve and valve-in-ring: Technical aspects and procedural outcomes,” EuroIntervention, vol. 12, pp. Y93-Y96, 2016. [cited by applicant]
Biaggi, Patric et al “Hybrid Imaging During Transcatheter Structural Heart Interventions,” Curr. Cardiovasc. Imaging Rep., vol. 8, No. 9, 2015. [cited by applicant]
Wilbring, Manuel et al “Transapical Transcatheter Valve-in-Valve Implantation for Deteriorated Mitral Valve Bioprostheses,” Ann Thorac Surg, vol. 95, pp. 111-118, 2013. [cited by applicant]
Bartel, Thomas, “Three-dimensional printing for quality management in device closure of interatrial communications,” Eur. Hear. J.—Cardiovasc. Imaging, 2016. [cited by applicant]
Brezezinski, M. et al “The New 3D Printed Left Atrial Appendage Closure with a Novel Holdfast Device: A Pre-Clinical Feasibility Animal Study,” PLoS One, vol. 11, No. 5, 2016. [cited by applicant]
Olivieri, Laura J. “Three-dimensional printing of intracardiac defects from three-dimensional echocardiographic images: Feasibility and relative accuracy,” J. Am. Soc. Echocardiogr., vol. 28, No. 4, pp. 392-397, 2015. [cited by applicant]
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