IP Library Granted Patent US 11,744,544
Granted Patent B2
US 11,744,544 · App. 17/469,195 · Granted Sep 5, 2023

Devices, systems, and methods for vessel assessment

Inventors: David M. Sheehan (Poway, CA); Bernhard Sturm (Davis, CA)
Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
A61B8/12A61B5/0095A61B5/02007A61B5/0215A61B5/4848A61B5/7425A61B6/032A61B6/037A61B6/4417A61B6/463A61B6/504A61B6/5247A61B8/0883A61B8/0891A61B8/4416G01R33/34084G01R33/48G06T7/0016A61B5/0035A61B5/0066A61B5/055A61B5/1075A61B5/1076A61B5/1079A61B2090/364A61F2/82G01R33/285G01R33/4808G01R33/5635G06T2207/30104
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Quick Facts
Patent No.
US 11,744,544
App. No.
17/469,195
Granted
Sep 5, 2023
Kind
B2
Abstract

Devices, systems, and methods for visually depicting a vessel and evaluating a physiological condition of the vessel are disclosed. One embodiment includes obtaining, at a first time, a first image of the vessel, the image being in a first medical modality, and obtaining, at a second time subsequent to the first time, a second image of the vessel, the image being in the first medical modality. The method also includes spatially co-registering the first and second images and outputting a visual representation of the co-registered first and second images on a display. Further, the method includes determining a physiological difference between the vessel at the first time and the vessel at the second time based on the co-registered first and second images, and evaluating the physiological condition of the vessel of the patient based on the determined physiological difference.

Claims (44)

1. A system for evaluating a vessel of a patient, comprising:

a processor configured to:

receive a first image of the vessel obtained from an imaging device during a first procedure, wherein the first image depicts a same location of the vessel with a first vessel structure;

receive a second image of the vessel obtained from the imaging device during a different, second procedure performed subsequent to the first procedure and subsequent to a therapeutic procedure directed to the same location, wherein the second image depicts the same location with a different, second vessel structure resulting from a physiological change caused by the therapeutic procedure, wherein the therapeutic procedure comprises at least one of percutaneous coronary intervention (PCI), angioplasty, stenting, coronary artery graft, ablation, cryotherapy, atherectomy, or administration of a drug, wherein the first image and the second image comprise a same imaging modality and a same view of the vessel;

positionally align the first image and the second image such that the same location is in the same position in each of the first and second images;

receive a user input selecting the same location in the first image such that the first vessel structure is identified;

identify, based on the user input and the positional alignment of the first and second images, the same location in the second image;

generate a screen display comprising:

the first image;

a first marker overlaid on the first image proximate to the same location such that the same location with the first vessel structure is visually indicated;

the second image displayed simultaneously as the first image and spaced from the first image; and

a second marker overlaid on the second image proximate to the same location such that the same location with the different, second vessel structure resulting from the physiological change caused by the therapeutic procedure is visually indicated in the second image; and

output the screen display on a display.

2. The system of claim 1 ,

wherein the first image and the second image depict a length of the vessel, and

wherein the same location indicated by the first marker in the first image and the second marker in the second image is a location along the length of the vessel.

3. The system of claim 1 , wherein the first image and the second image are extraluminal images.

4. The system of claim 3 , wherein the first image and the second image comprise one of: an x-ray image, an angiogram image, an ultrasound image, a two-dimensional computed tomography (CT) image, a three-dimensional CT image, a computed tomography angiogram (CTA) image, a positron emission tomography (PET) image, a PET-CT image, a magnetic resonance image (MRI), or a single-photon emission computed tomography (SPECT) image.

5. The system of claim 1 , wherein the first image and the second image are endoluminal images.

6. The system of claim 5 , wherein the first image and the second image comprise one of: an intravascular ultrasound (IVUS) image, a forward looking IVUS (FL-IVUS) image, an intravascular photoacoustic (IVPA) image, a near-infrared Spectroscopy (NIRS) image, an optical coherence tomography (OCT) image, an intracardiac echocardiography (ICE) image, a forward-looking ICE (FLICE) image, or an intravascular magnetic resonance image (MRI).

7. The system of claim 1 , further comprising the imaging device.

8. The system of claim 7 , wherein the imaging device comprises an extraluminal imaging device.

9. The system of claim 7 , wherein the imaging device comprises an endoluminal imaging device.

10. The system of claim 1 , wherein the processor is further configured to:

receive a third image of the vessel obtained from an additional imaging device during the first procedure, wherein the third image depicts the same location with the first vessel structure;

receive a fourth image of the vessel obtained from the additional imaging device during the second procedure, wherein the fourth image depicts the same location with the second vessel structure; and

positionally align the third image and the fourth image such that the same location is in the same position in each of the third and fourth images,

wherein the first and second images comprise a first imaging modality and the third and fourth images comprise a different, second imaging modality.

11. The system of claim 10 , wherein the screen display further comprises:

the third image positioned proximate to the first image; and

the fourth image positioned proximate to the second image.

12. The system of claim 1 , wherein the processor is configured to:

determine, based on the first image and the second image, the physiological change between the first and second vessel structures; and

output a report to the display indicating the physiological change.

13. The system of claim 12 , wherein the report comprises an indication of a difference between a first diameter of the vessel associated with the first vessel structure and a second diameter of the vessel associated with the second vessel structure.

14. The system of claim 1 , wherein the processor is configured to generate a composite image by overlaying the first image and the second image, and wherein the screen display comprises the composite image.

15. The system of claim 1 , wherein the processor is further configured to:

determine, based on first proximal pressure data and first distal pressure data obtained from the vessel during the first procedure, a first pressure ratio corresponding to the first vessel structure; and

determine, based on second proximal pressure data and second distal pressure data obtained from the vessel during the second procedure, a second pressure ratio corresponding to the second vessel structure.

16. The system of claim 15 , wherein the screen display further comprises:

a first representation of the first pressure ratio positioned proximate to the first image; and

a second representation of the second pressure ratio positioned proximate to the second image.

17. The system of claim 15 , wherein the first pressure ratio and the second pressure ratio are one of: a fractional flow reserve (FFR), Pd/Pa, or instantaneous wave free ratio (iFR).

18. The system of claim 1 , wherein the first marker and the second marker comprise a same shape.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 1, 2022
From: KONINKLIJKE PHILIPS N.V.
To: PHILIPS IMAGE GUIDED THERAPY CORPORATION
Reel/Frame 058521/0526 →
Continuity (3)
Continuation 14702940 · May 4, 2015
Provisional Application 61989219 · May 6, 2014
Related Publication 20210401400A1 · Dec 30, 2021
Cited By (10)
US 12,315,076 US 12,354,755 US 12,387,325 US 12,408,885 US 12,423,813 US 12,446,965 US 12,499,646 US 12,512,196 US 12,531,159 US 12,567,489