IP Library › Granted Patent US 12,347,100
Granted Patent B2
US 12,347,100 · App. 17/490,895 · Granted Jul 1, 2025

Systems and methods for generating virtual images

Inventors: Yizhaq Shmayahu (Ramat HaSharon, IL); Diego Merkier (Bat Hefer, IL)
Assignee: Mazor Robotics Ltd.
G06T7/0012A61B34/30G06T7/13G06T2207/10116G06T2207/10132G06T2207/30012
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Quick Facts
Patent No.
US 12,347,100
App. No.
17/490,895
Granted
Jul 1, 2025
Kind
B2
Abstract

A method of generating a virtual MRI image includes receiving an initial MRI image of a patient in a first position, the initial MRI image depicting at least a portion of an anatomy of the patient; receiving a plurality of images of the patient in a second position, each of the plurality of images depicting at least a plurality of bony elements within the portion of the patient's anatomy; receiving soft tissue information corresponding to at least a plurality of soft tissue elements within the portion of the patient's anatomy; segmenting the initial MRI image to identify a depiction of each of the plurality of bony elements and each of the plurality of soft tissue elements within the initial MRI image; and generating a virtual MRI image based on the MRI image, the plurality of images, and the soft tissue information.

Claims (46)

1. A method of generating a virtual magnetic resonance imaging (MRI) image, the method comprising:

receiving, from an MRI imaging device, an initial preoperative MRI image of a patient in a supine position, the initial preoperative MRI image depicting at least a portion of an anatomy of the patient;

receiving, from an imaging device different from the MRI imaging device, a plurality of intraoperative images of the patient in a prone position, each of the plurality of intraoperative images depicting at least a plurality of bony elements within the portion of the patient's anatomy;

segmenting the initial preoperative MRI image to identify a depiction of each of the plurality of bony elements and each of a plurality of soft tissue elements within the initial preoperative MRI image, wherein the segmenting enables each of the plurality of soft tissue elements to be modified relative to one another within the initial preoperative MRI image;

determining a range of deformation and a range of movement of one or more elements of the plurality of bony elements;

generating the virtual MRI image based on the initial preoperative MRI image, the plurality of intraoperative images of the patient in the prone position, and a biomechanical model corresponding to at least the plurality of soft tissue elements associated with the patient, wherein generating the virtual MRI image comprises modifying a first soft tissue element of the plurality of soft tissue elements using the biomechanical model without modifying a second soft tissue element of the plurality of soft tissue elements; and

guiding, using the virtual MRI image, a robotic arm relative to the anatomy of the patient.

2. The method of claim 1 , wherein generating the virtual MRI image comprises:

registering each of the plurality of bony elements in the initial preoperative MRI image to a corresponding one of the plurality of bony elements depicted in each of the plurality of intraoperative images.

3. The method of claim 1 , wherein generating the virtual MRI image further comprises:

updating, based on the range of deformation and the range of movement, the biomechanical model.

4. The method of claim 1 , wherein the biomechanical model comprises ultrasound information corresponding to at least some of the portion of the patient's anatomy.

5. The method of claim 1 , wherein the plurality of intraoperative images provides orthogonal views of the portion of the patient's anatomy.

6. The method of claim 1 , wherein the virtual MRI image is generated without the patient being imaged by the MRI imaging device when in the prone position.

7. The method of claim 1 , wherein the plurality of intraoperative images comprises at least one X-ray image.

8. The method of claim 1 , wherein the plurality of intraoperative images comprises at least one ultrasound image.

9. A system for generating a virtual magnetic resonance imaging (MRI) image, the system comprising:

an imaging device capable of imaging hard tissue;

a processor; and

a memory storing instructions for execution by the processor that, when executed, cause the processor to:

receive, from an MRI imaging device, a first MRI image of a patient in a supine position, the first MRI image depicting hard tissue and soft tissue of the patient;

receive a plurality of images of the patient in a prone position different than the supine position, the plurality of images generated by the imaging device that is different from the MRI imaging device, wherein the patient is in the supine position preoperatively, and wherein the patient is in the prone position intraoperatively;

receive soft tissue information corresponding to the patient;

process the first MRI image to identify a plurality of bony elements and a plurality of soft tissue elements therein, wherein the processing enables each of the plurality of soft tissue elements to be modified relative to one another within the first MRI image;

determine a range of deformation and a range of movement of one or more bony elements of the plurality of bony elements;

generate a virtual second MRI image by registering each of the plurality of bony elements in the first MRI image to a corresponding bony element in the plurality of images, and by updating the plurality of soft tissue elements in the first MRI image based on the soft tissue information corresponding to the patient, wherein updating the plurality of soft tissue elements comprises modifying a first soft tissue element of the plurality of soft tissue elements using the soft tissue information without modifying a second soft tissue element of the plurality of soft tissue elements; and

guide, using the virtual second MRI image, a robotic arm relative to the patient.

10. The system of claim 9 , further comprising:

an ultrasound probe; and

a second robotic arm configured to manipulate at least one of the imaging device and the ultrasound probe.

11. The system of claim 10 , wherein the instructions stored in the memory, when executed, further cause the processor to:

cause the second robotic arm to move the ultrasound probe to a plurality of positions to generate the soft tissue information.

12. The system of claim 9 , wherein each of the plurality of bony elements is a vertebra.

13. The system of claim 9 , wherein the plurality of soft tissue elements comprises at least one of a ligament and an intervertebral disc.

14. The system of claim 9 , wherein the soft tissue information comprises a biomechanical model.

15. A method of modifying image data, the method comprising:

receiving first image data corresponding to a patient's spine in a supine position, the first image data comprising first information about a plurality of bony elements of the patient's spine and a plurality of soft tissue elements of the patient's spine, wherein the first image data is generated preoperatively;

receiving second image data corresponding to at least two images of the patient's spine in a prone position different than the supine position, the second image data comprising second information about the plurality of bony elements of the patient's spine, wherein the second image data is generated intraoperatively;

receiving soft tissue data corresponding to the plurality of soft tissue elements of the patient's spine;

determining a range of deformation and a range of movement of one or more bony elements of the plurality of bony elements;

generating third image data by modifying the first image data based on the second image data and the soft tissue data, the modifying comprising registering the first information to the second information and further comprising changing a first soft tissue element of the plurality of soft tissue elements using the soft tissue data without changing a second soft tissue element of the plurality of soft tissue elements; and

guiding, using the third image data, a robotic arm relative to the patient's spine.

16. The method of claim 15 , wherein the first image data is generated using magnetic resonance imaging, and wherein the second image data is generated without using the magnetic resonance imaging.

17. The method of claim 15 , wherein the at least two images are offset by at least thirty degrees.

18. The method of claim 15 , wherein the at least two images are orthogonal.

19. The method of claim 15 , wherein the first image data is in a first format, the second image data is in a second format different than the first format, and the third image data corresponds to a virtual image in the first format of the patient's spine in the prone position.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 30, 2021
From: SHMAYAHU, YIZHAQ; MERKIER, DIEGO
To: MAZOR ROBOTICS LTD.
Reel/Frame 057660/0526 →
Continuity (2)
Provisional Application 63116003 · Nov 19, 2020
Related Publication 20220156928A1 · May 19, 2022
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