IP Library Granted Patent US 12,203,085
Granted Patent B2
US 12,203,085 · App. 17/551,455 · Granted Jan 21, 2025

3'UTR sequence for transgene expression

Inventors: Sandeep Kumar (Johnston, IA); Sara Bennett (Indianapolis, IN); Andrew J. Bowling (Indianapolis, IN); Alicia Walker (Indianapolis, IN); Cory M. Larsen (Zionsville, IN); Heather Pence (Indianapolis, IN); Staci Weaver (Indianapolis, IN); Ronnie Hampton, Jr. (Indianapolis, IN)
Assignee: CORTEVA AGRISCIENCE, LLC
C12N15/8233A01H6/604
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Quick Facts
Patent No.
US 12,203,085
App. No.
17/551,455
Granted
Jan 21, 2025
Kind
B2
Abstract

This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a Glycine max egg cell gene. Some embodiments relate to a promoter or a 5′ UTR from a Glycine max egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3′ UTR or a terminator from a Glycine max egg cell gene that functions in plants to promote transcription of operably linked nucleotide sequences.

Claims (9)

1. A nucleic acid vector comprising a 3′ UTR operably linked to: a) a heterologous polylinker sequence; or b) a non- Glycine max egg cell polynucleotide sequence, wherein said 3′ UTR comprises a polynucleotide sequence that has at least 97% sequence identity with SEQ ID NO:3.

2. The nucleic acid vector of claim 1 , wherein said 3′ UTR is 739 bp in length.

3. The nucleic acid vector of claim 1 , wherein said 3′ UTR consists of a polynucleotide sequence that has at least 97% sequence identity with SEQ ID NO:3.

4. The nucleic acid vector of claim 1 , further comprising a sequence encoding a selectable maker.

5. The nucleic acid vector of claim 1 , wherein said non- Glycine max egg cell polynucleotide sequence is a transgene.

6. The nucleic acid vector of claim 1 , wherein the transgene encodes a selectable marker or a gene product conferring insecticidal resistance, herbicide tolerance, expression of an RNAi, nitrogen use efficiency, water use efficiency, or nutritional quality.

7. The nucleic acid vector of claim 1 , further comprising a promoter polynucleotide sequence of SEQ ID NO:2, wherein the promoter sequence is operably linked to said polylinker or said non- Glycine max egg cd polynucleotide sequence.

8. The nucleic acid vector of claim 7 , further comprising an intron sequence.

9. The nucleic acid vector of claim 7 , wherein said promoter has tissue preferred specific expression.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2021
From: KUMAR, SANDEEP; BENNETT, SARA; BOWLING, ANDREW J.; WALKER, ALICIA; LARSEN, CORY M.; PENCE, HEATHER; WEAVER, STACI; HAMPTON, RONNIE, JR.
To: DOW AGROSCIENCES LLC
Reel/Frame 058395/0835 →
CHANGE OF NAME Recorded Dec 15, 2021
From: DOW AGROSCIENCES LLC
To: CORTEVA AGRISCIENCE LLC
Reel/Frame 058965/0917 →
Continuity (3)
Continuation 16139112 · Sep 24, 2018
Provisional Application 62567836 · Oct 4, 2017
Related Publication 20220098606A1 · Mar 31, 2022
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