IP Library › Granted Patent US 12,599,694
Granted Patent B2
US 12,599,694 · App. 17/718,121 · Granted Apr 14, 2026

Scaffold wound dressing

Inventor: Mehrdad Mark Mofid (San Diego, CA)
Assignee: SYLKE, INC.
A61L15/32A61L15/40A61L15/58A61L2300/64
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Quick Facts
Patent No.
US 12,599,694
App. No.
17/718,121
Filed
Apr 11, 2022
Granted
Apr 14, 2026
Kind
B2
Examiner
SAEED, ALI S
Art Unit
1616
USPC
424/445
Abstract

Disclosed is an external wound dressing formed of a bioprotein scaffolding that may include a pressure-sensitive adhesive impregnated in the bioprotein scaffolding. A method of wound treatment can include adhering an external wound dressing formed of a bioprotein scaffolding to an external injury site. Another method can include applying an adhesive to the skin of a patient, placing an external wound dressing formed of a bioprotein scaffolding over an injury site on the skin of the patient, and applying a sealing adhesive on top of the bioprotein scaffolding. Yet another method can include applying an adhesive to the skin of a patient, placing an external wound dressing formed of a bioprotein scaffolding over an injury site on the skin of the patient that has not been stitched, and applying a sealing adhesive on top of the bioprotein scaffolding.

Claims (15)

1 . An apparatus comprising:

an external wound dressing configured to be adhered to skin over a wound and to prevent wound separation, the external wound dressing formed of an animal-derived bioprotein scaffolding of sufficient strength to prevent wound separation, wherein the animal-derived bioprotein scaffolding consists of bioprotein fibers woven together to form regular or semi-regular boundaries of interstitial spaces, and a pressure-sensitive adhesive impregnated in the bioprotein scaffolding for directly adhering the animal-derived bioprotein scaffolding to the skin to prevent wound separation.

2 . The apparatus of claim 1 , wherein the bioprotein fibers are an insect-derived bioprotein.

3 . The apparatus of claim 2 , wherein the bioprotein fibers are a silk bioprotein.

4 . The apparatus of claim 3 , wherein the silk bioprotein is obtained from Bombyx mori silkworms.

5 . The apparatus of claim 4 , wherein the silk bioprotein has a reduced amount of sericin relative to the amount of sericin naturally present in the silk bioprotein.

6 . The apparatus of claim 1 , wherein the adhesive is included within the interstitial spaces.

7 . The apparatus of claim 1 , further comprising a sealing adhesive on top of the animal-derived bioprotein scaffolding.

8 . The apparatus of claim 7 , wherein the sealing adhesive comprises cyanoacrylate.

9 . The apparatus of claim 1 , wherein the bioprotein fibers are multiple silk protein filaments combined by helical twisting to form a multi-filament bioprotein fiber.

10 . The apparatus of claim 1 , wherein the boundaries of the interstitial spaces have an area or dimension that varies by no more than 5%.

11 . The apparatus of claim 1 , wherein the boundaries of the interstitial spaces have an area or dimension that varies by no more than 20%.

12 . The apparatus of claim 1 , wherein the pressure-sensitive adhesive is an Aqueous 98:2 n-butylacrylate: hydroxy-methacrylate emulsion.

13 . The apparatus of claim 1 , wherein the bioprotein scaffolding is formed into a roll from which specific-sized portions may be cut.

14 . The apparatus of claim 1 , wherein the pressure-sensitive adhesive is an acrylic material making the pressure-sensitive adhesive a waterproof pressure sensitive adhesive that causes the external wound dressing to retain more adhesion in the presence of water than a non-waterproof pressure-sensitive adhesive.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2024
From: MOFID, M. MARK
To: SYLKE, INC.
Reel/Frame 068271/0862 →
Continuity (3)
Continuation 17102257 · Nov 23, 2020
Continuation In Part 17100675 · Nov 20, 2020
Related Publication 20220233742A1 · Jul 28, 2022
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