IP Library Granted Patent US 12,599,742
Granted Patent B2
US 12,599,742 · App. 17/738,285 · Granted Apr 14, 2026

Systems and methods for high velocity nasal insufflation

Inventors: Scott A. Leonard (Exeter, NH); Brian Green (Exeter, NH); John Allen (Exeter, NH); David Adams (Exeter, NH); Marc Gervais (Exeter, NH); Mark Kolnsberg (Exeter, NH); Richelle Helman (Exeter, NH)
Assignee: VAPOTHERM, INC.
A61M16/142A61M16/0066A61M16/0096A61M16/0672A61M16/101A61M16/16A61M16/162A61M16/20A61M2016/0027A61M2016/003A61M16/0069A61M16/0666A61M2016/1025A61M16/201A61M2202/0208A61M2205/0272
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Quick Facts
Patent No.
US 12,599,742
App. No.
17/738,285
Granted
Apr 14, 2026
Kind
B2
Abstract

Systems, methods, and devices for humidifying a breathing gas are presented. The system includes a base unit, a vapor transfer unit, a nasal cannula, and a liquid container. The base unit includes a blower. The vapor transfer unit is external to the base unit and includes a gas passage, a liquid passage, a gas outlet, and a membrane separating the gas passage and the liquid passage. The membrane permits transfer of vapor into the gas passage from liquid in the liquid passage. The nasal cannula is coupled to the gas outlet. The liquid container is configured to reversibly mate with the base unit.

Claims (29)

1 . A system for delivering breathing gas to a patient, the system comprising:

a base unit comprising a blower;

a vapor transfer unit external to the base unit and comprising:

a gas passage,

a liquid passage,

a gas outlet, and

a membrane separating the gas passage and the liquid passage, wherein the membrane permits transfer of vapor into the gas passage from liquid in the liquid passage;

a nasal cannula coupled to the gas outlet;

a connector in fluid communication with the blower and the vapor transfer unit, the connector comprising a breathing gas inlet disposed downstream of the blower, a breathing gas outlet disposed upstream of the vapor transfer unit, and an auxiliary port disposed downstream of the breathing gas inlet and upstream of the breathing gas outlet and configured to receive a nebulized medicament, the connector configured to deliver the medicament and the breathing gas to the patient simultaneously; and

a liquid container configured to reversibly mate with the base unit.

2 . The system of claim 1 , wherein the liquid container interlocks with a surface of the base unit.

3 . The system of claim 1 , wherein the container has a surface formed of a flexible film.

4 . The system of claim 3 , wherein the base unit further comprises a heating element for heating liquid, the heating element having a heating surface.

5 . The system of claim 4 , wherein the flexible film is configured to mate with the heating surface when the liquid container mates with the base unit.

6 . The system of claim 3 , wherein base unit includes a pressure sensor configured to measure pressure of the liquid in the liquid container when the liquid container is coupled to the base unit.

7 . The system of claim 6 , wherein the pressure sensor is configured to measure pressure against the flexible film.

8 . The system of claim 1 , wherein the blower is configured to pressurize breathing gas to less than about 276 kPa (40 psi).

9 . The system of claim 1 , wherein the liquid container includes an impeller.

10 . The system of claim 9 , wherein the base unit includes a motor.

11 . The system of claim 10 , wherein the motor is magnetically coupled to the impeller.

12 . The system of claim 1 , wherein the liquid passage is coupled to the liquid container by a first tube.

13 . The system of claim 12 , wherein the gas passage is coupled to the blower by a second tube.

14 . The system of claim 13 , wherein the first tube passes within the second tube.

15 . The system of claim 13 , wherein the second tube has an inner diameter of more than about 5 mm.

16 . The system of claim 1 , wherein the membrane is non-porous.

17 . The system of claim 1 , wherein the nasal cannula includes an outlet having a cross sectional area less than a cross sectional area of a patient's nostril.

18 . The system of claim 1 , wherein the base unit further comprises an oxygen sensor.

19 . The system of claim 1 , further comprising an oxygen source or an oxygen concentrator.

20 . The system of claim 19 , wherein the oxygen source comprises and oxygen outlet, and wherein the blower comprises a blower inlet, the oxygen outlet being coupled to the blower inlet.

Assignments (2)
SECURITY INTEREST Recorded Apr 20, 2026
From: VAPOTHERM, INC.
To: PERCEPTIVE CAPITAL SOLUTIONS HOLDINGS LP
Reel/Frame 075477/0224 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2025
From: LEONARD, SCOTT A.; GREEN, BRIAN; ALLEN, JOHN; ADAMS, DAVID; GERVAIS, MARC; KOLNSBERG, MARK; HELMAN, RICHELLE
To: VAPOTHERM, INC.
Reel/Frame 073115/0742 →
Continuity (3)
Continuation 15783566 · Oct 13, 2017
Provisional Application 62408560 · Oct 14, 2016
Related Publication 20220265953A1 · Aug 25, 2022
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