Alcohol-free hydrogen peroxide disinfectant compositions and methods of use thereof
An aqueous-based disinfecting composition is disclosed. The composition can include hydrogen peroxide at a concentration of 0.1 to 0.9% w/w, caprylic acid, or a salt thereof, at a concentration of 0.1 to 1% w/w, salicylic acid, or a salt thereof at a concentration of 0.1 to 1% w/w, and water. The composition does not include or is substantially free of a volatile C1-C7 alcohol, and the pH of the composition is from about 0.1 to about 6, and the composition is capable of exhibiting mycobactericidal activity against mycobacteria on a surface when the composition is in contact with the mycobacteria for at least 1 minute.
1. An aqueous-based disinfecting composition comprising:
(a) hydrogen peroxide at a concentration of 0.1 to 0.9% w/w;
(b) caprylic acid, or a salt thereof, at a concentration of 0.1 to 1% w/w;
(c) salicylic acid, or a salt thereof at a concentration of 0.1 to 1% w/w; and
(d) water,
wherein the composition does not include or is substantially free of a volatile C1-C7 alcohol, wherein the pH of the composition is from about 0.1 to 2, and wherein the composition is capable of exhibiting mycobactericidal activity against mycobacteria on a surface when the composition is in contact with the mycobacteria for at least 1 minute.
2. The composition of claim 1 , wherein the surface is a non-porous hard surface.
3. The composition of claim 1 , wherein the composition further comprises a sequestering or chelating agent.
4. The composition of claim 3 , wherein the sequestering or chelating agent is etidronic acid (HEDP), or a salt thereof, and is at a concentration of about 0.01 to about 5% w/w.
5. The composition of claim 1 , wherein the composition further comprises one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or a salt thereof.
6. The composition of claim 5 , wherein the one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or a salt thereof, is formic acid, or a salt thereof, at a concentration of about 0.01 to about 5% w/w.
7. The composition of claim 1 , wherein the composition further comprises one or more surfactants selected from sodium olefin sulfonate surfactants, sodium C8 to C16 alkyl sulfate surfactants, or C12 to C16 linear alkyl ether carboxylic acids, or salts thereof.
8. The composition of claim 7 , wherein the sodium olefin sulfonate surfactant is sodium C14-C16 olefin sulfonate at a concentration of about 0.01 to about 5% w/w.
9. The composition of claim 7 , wherein the C8 to C16 alkyl sulfate surfactant is sodium lauryl sulfate at a concentration of about 0.01 to about 5% w/w.
10. The composition of claim 7 , wherein the C12 to C16 linear alkyl ether carboxylic acids, or salts thereof, is laureth-5 carboxylic acid, or a salt thereof, at a concentration of about 0.01 to about 5% w/w.
11. The composition of claim 1 , wherein the composition further comprises a fragrance or a dye.
12. The composition of claim 1 , wherein the hydrogen peroxide is at a concentration of 0.3 to 0.7% w/w.
13. A method of disinfecting or sterilizing a non-porous hard surface, the method comprising:
contacting the non-porous hard surface with the composition of claim 1 ; and
allowing the composition to remain in contact with the non-porous hard surface for at least 1 minute, thereby disinfecting or sterilizing the non-porous hard surface.
14. A method of disinfecting or sterilizing a non-porous hard surface, the method comprising:
(1) contacting the non-porous hard surface with a composition comprising:
(a) hydrogen peroxide at a concentration of 0.1 to 0.9% w/w;
(b) one or more linear monocarboxylic acids with a carbon chain length of C5 to C12, or a salt thereof, at a concentration of about 0.01 to about 5% w/w;
(c) salicylic acid at a concentration of about 0.01 to about 5% w/w; and
(d) water; and
(2) allowing the composition to remain in contact with the non-porous hard surface for at least 1 minute, thereby disinfecting or sterilizing the non-porous hard surface, wherein the composition does not contain or is substantially free of a volatile C1-C7 alcohol,
wherein the one or more linear monocarboxylic acids with a carbon chain length of C5 to C12, or a salt thereof, is caprylic acid (C8), or a salt thereof, and/or capric acid (C10), or a salt thereof, and wherein the pH of the composition is from about 0.1 to 2.
15. The method of claim 14 , wherein the composition further comprises a sequestering or chelating agent.
16. The method of claim 15 , wherein the sequestering or chelating agent is etidronic acid (HEDP), or a salt thereof, and is at a concentration of about 0.01 to about 5% w/w.
17. The method of claim 14 , wherein the composition further comprises one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or a salt thereof.
18. The method of claim 17 , wherein the one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or the salt thereof, is formic acid, or a salt thereof, at a concentration of about 0.01 to about 5% w/w.
19. The method of claim 14 , wherein the composition further comprises one or more surfactants selected from sodium olefin sulfonate surfactants, sodium C8 to C16 alkyl sulfate surfactants, or C12 to C16 linear alkyl ether carboxylic acids, or salts thereof.
20. The method of claim 14 , wherein the non-porous hard surface is at least a portion of the surface of a counter, a furniture, a wall, a floor, a medical equipment, a device, a tool, an instrument, a food preparation or handling equipment, an appliance, a utensil, or a bathroom fixture.
21. The method of claim 14 , wherein the non-porous hard surface is not skin or a biological surface.