IP Library › Granted Patent US 12,630,798
Granted Patent B2
US 12,630,798 · App. 17/936,904 · Granted May 19, 2026

Culture devices

Inventor: Xuan Wang (Shanghai, CN)
Assignee: SHANGHAI RUIYU BIOTECH CO., LTD.
C12M29/04C12M23/38C12M23/48C12M33/04C12M33/14
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,630,798
App. No.
17/936,904
Granted
May 19, 2026
Kind
B2
Abstract

One or more embodiments of the present disclosure relate to a culture device, which comprises: an accommodation base, an accommodation chamber disposed on the accommodation base. The accommodation chamber includes a culture chamber for accommodating one or more cultures. The culture chamber includes a chamber bottom wall and a chamber side wall surrounding the chamber bottom wall. A culture solution channel is formed between an outer side of the chamber side wall and an inner wall of the accommodation chamber. At least part of the chamber side wall includes a membrane material, and a plane where the membrane material is located intersect with the chamber bottom wall.

Claims (36)

1 . A culture device, comprising:

an accommodation base, wherein an accommodation chamber is disposed on the accommodation base and includes a culture chamber for accommodating a culture, wherein

the culture chamber includes one or more U-shaped culture sub-chambers, a chamber bottom wall and a chamber side wall surrounding the chamber bottom wall; wherein

a culture solution channel is formed between an outer side of the chamber side wall and an inner wall of the accommodation chamber;

the culture solution channel includes a U-shaped channel surrounding the one or more U-shaped sub-chambers; and

at least a part of the chamber side wall includes a membrane material, a plane where the membrane material is located intersecting with the chamber bottom wall.

2 . The culture device of claim 1 , wherein a projected area on the chamber bottom wall projected by the membrane material in a direction perpendicular to the chamber bottom wall does not exceed 50% of an area of the chamber bottom wall.

3 . The culture device of claim 1 , wherein the culture chamber further includes a support frame defining an external contour of the culture chamber, the chamber bottom wall and the chamber side wall being fixed relative to the support frame.

4 . The culture device of claim 1 , wherein the chamber side wall includes a hollow-out plate and the membrane material is attached to the hollow-out plate.

5 . The culture device of claim 3 , wherein the membrane material is fixed on the support frame by a physical connection.

6 . The culture device of claim 3 , wherein the support frame includes four support columns, wherein

an end of each of the four support columns is fixed relative to an end of another one of the four support columns.

7 . The culture device of claim 1 , wherein the accommodation base includes a first drainage component extending from the inner wall of the accommodation chamber into a U-shaped notch formed by one of the one or more U-shaped culture sub-chambers.

8 . The culture device of claim 1 , wherein:

the one or more U-shaped culture sub-chambers include at least two culture sub-chambers, and

the accommodation base includes a second drainage component extending from the inner wall of the accommodation chamber into a U-shaped notch formed by two adjacent U-shaped culture sub-chambers of the at least two culture sub-chambers.

9 . The culture device of claim 1 , wherein one or more isolation components are disposed in the culture chamber to separate the culture chamber into two or more culture sub-chambers, at least a part of the one or more isolation components including the membrane material.

10 . The culture device of claim 3 , wherein the accommodation base includes a locking component configured to limit a movement of the support frame on a bottom wall of the accommodation chamber.

11 . The culture device of claim 10 , wherein the support frame includes a support body and a limiting component, the limiting component being connected with one end of the support body, wherein:

the locking component is matched with the limiting component, and

a matching of the locking component and the limiting component limits the movement of the support frame on the bottom wall of the accommodation chamber.

12 . The culture device of claim 11 , wherein:

the limiting component and the support body form a member with a T-shape, an L-shape, an H-shape, or a cross shape, and

the accommodation chamber on the accommodation base is a groove matched with the member.

13 . The culture device of claim 11 , wherein the support body includes a bottom plate, one end of the bottom plate being fixedly connected with the limiting component.

14 . The culture device of claim 13 , wherein the support body further includes a top plate, wherein

there is a certain distance between the bottom plate and the top plate, and

one end of the top plate is fixedly connected with the limiting component.

15 . The culture device of claim 14 , wherein the support body further includes a side plate opposite to the limiting component, another end of the top plate and another end of the bottom plate being connected with the side plate.

16 . The culture device of claim 14 , wherein one or more chamber side walls between the top plate and the bottom plate of the support body include the membrane material.

17 . The culture device of claim 11 , wherein a ratio of a width of the support body to a width of the accommodation chamber is within a range of 0.1-0.9.

18 . The culture device of claim 14 , wherein one end and another end of the top plate are respectively provided with a culture outlet and a culture inlet.

19 . The culture device of claim 18 , wherein the culture device further includes an upper cover, wherein

the upper cover is provided with a culture inoculation port, a culture solution inlet, and a culture solution outlet, wherein

the culture inoculation port corresponds to the culture outlet and the culture inlet; and

the culture solution inlet and the culture solution outlet communicate with the culture solution channel.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 25, 2022
From: WANG, XUAN
To: SHANGHAI RUIYU BIOTECH CO., LTD.
Reel/Frame 061879/0278 →
Priority Claims (2)
CN 202111170828.8 · Oct 8, 2021 · national
CN 202122420855.8 · Oct 8, 2021 · national
Continuity (1)
Related Publication 20230113710A1 · Apr 13, 2023
References Cited (35)
US 4748124A · Vogler · 1988 [cited by examiner]
US 4940547A · Cho · 1990 [cited by examiner]
US 4990256A · Schmidt · 1991 [cited by examiner]
US 5462874A · Wolf et al. · 1995 [cited by applicant]
US 6228607B1 · Kersten · 2001 [cited by examiner]
US 10087422B2 · Ingber · 2018 [cited by examiner]
US 20070042490A1 · Welter · 2007 [cited by examiner]
US 20080194017A1 · Esser · 2008 [cited by examiner]
US 20090298164A1 · Cattadoris et al. · 2009 [cited by applicant]
US 20110044865A1 · Groisman · 2011 [cited by examiner]
US 20110306081A1 · Szita · 2011 [cited by examiner]
US 20120135452A1 · Shuler · 2012 [cited by examiner]
US 20130005027A1 · Paullier et al. · 2013 [cited by applicant]
US 20130059322A1 · Hung · 2013 [cited by examiner]
US 20130143230A1 · Tolias · 2013 [cited by examiner]
US 20180031564A1 · Su · 2018 [cited by examiner]
US 20180326417A1 · Wikswo · 2018 [cited by examiner]
US 20180327702A1 · Gannon · 2018 [cited by examiner]
US 20190048305A1 · De et al. · 2019 [cited by applicant]
US 20200123488A1 · McCain · 2020 [cited by examiner]
US 20210318226A1 · Handique · 2021 [cited by examiner]
US 20220362772A1 · Wang · 2022 [cited by examiner]
US 20230381773A1 · Takahashi · 2023 [cited by examiner]
CN 206385177U · 2017 [cited by applicant]
CN 210826140U · 2020 [cited by applicant]
CN 216663114U · 2022 [cited by applicant]
DE 202018000370U1 · 2018 [cited by applicant]
EP 0363262A1 · 1990 [cited by applicant]
EP 2955220A1 · 2015 [cited by applicant]
FR 1448148A · 1966 [cited by applicant]
JP 2011206045A · 2011 [cited by applicant]
WO 2012118799A2 · 2012 [cited by applicant]
WO 2015032889A1 · 2015 [cited by applicant]
WO 2018094003A1 · 2018 [cited by applicant]
The Extended European Search Report in European Application No. 22200447.5 mailed on Feb. 21, 2023, 9 pages. [cited by applicant]