IP Library › Granted Patent US 11,767,305
Granted Patent B2
US 11,767,305 · App. 18/077,966 · Granted Sep 26, 2023

Advantageous benzofuran compositions for mental disorders or enhancement

Inventor: Matthew Baggott (Redwood City, CA)
Assignee: Tactogen Inc
C07D307/81A61P25/18A61P25/24
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Quick Facts
Patent No.
US 11,767,305
App. No.
18/077,966
Granted
Sep 26, 2023
Kind
B2
Abstract

Pharmaceutically active benzofuran compositions for the treatment of mental disorders or for mental enhancement, including for entactogenic therapy. The present invention also includes benzofuran compounds, compositions, and methods for generally modulating central nervous system activity and treating central nervous system disorders.

Claims (46)

1. An enantiomerically enriched mixture of the S-enantiomer and R-enantiomer of a pair of enantiomers selected from those in a) through h) below, wherein the enantiomerically enriched mixture has between 55% and 90% S-enantiomer:

or a pharmaceutically acceptable salt or a mixed salt thereof.

2. The enantiomerically enriched mixture of claim 1 that has at least 60% S-enantiomer.

3. The enantiomerically enriched mixture of claim 1 that has at least 65% S-enantiomer.

4. The enantiomerically enriched mixture of claim 1 that has at least 70% S-enantiomer.

5. The enantiomerically enriched mixture of claim 1 that has at least 75% S-enantiomer.

6. The enantiomerically enriched mixture of claim 1 that has at least 80% S-enantiomer.

7. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

8. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

9. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

10. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

11. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

12. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

13. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

14. The enantiomerically enriched mixture of claim 1 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

15. An enantiomerically enriched mixture of the S-enantiomer and R-enantiomer of a pair of enantiomers selected from those in a) through h) below, wherein the enantiomerically enriched mixture has between 55% and 90% R-enantiomer:

or a pharmaceutically acceptable salt or a mixed salt thereof.

16. The enantiomerically enriched mixture of claim 15 that has at least 60% R-enantiomer.

17. The enantiomerically enriched mixture of claim 15 that has at least 65% R-enantiomer.

18. The enantiomerically enriched mixture of claim 15 that has at least 70% R-enantiomer.

19. The enantiomerically enriched mixture of claim 15 that has at least 75% R-enantiomer.

20. The enantiomerically enriched mixture of claim 15 that has at least 80% R-enantiomer.

21. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

22. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

23. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

24. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

25. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

26. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

27. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

28. The enantiomerically enriched mixture of claim 15 , wherein the mixture comprises

or a pharmaceutically acceptable salt or a mixed salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 5, 2023
From: BAGGOTT, MATTHEW
To: TACTOGEN INC
Reel/Frame 064157/0047 →
Continuity (9)
Continuation PCTUS2021036479 · Jun 8, 2021
Provisional Application 63165731 · Mar 24, 2021
Provisional Application 63149223 · Feb 13, 2021
Provisional Application 63062434 · Aug 6, 2020
Provisional Application 63055897 · Jul 23, 2020
Provisional Application 63048616 · Jul 6, 2020
Provisional Application 63046496 · Jun 30, 2020
Provisional Application 63036382 · Jun 8, 2020
Related Publication 20230150963A1 · May 18, 2023
Cited By (3)
US 12,344,591 US 12,365,661 US 12,454,515